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Displaying results 551 - 560 of 10000 in total
  1. Drug

    Cholecalciferol

    go.drugbank.com/drugs/DB00169
    ApprovedInvestigationalNutraceutical

    Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation … Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight [L5689].

    Mixtures: Escavite Lq, L-Methyl PNV DHAProducts: L-VIT D3 5000, COLECALCIFEROLO EG
  2. Drug

    Telmisartan

    go.drugbank.com/drugs/DB00966
    ApprovedInvestigational

    smooth muscle, ultimately leading to a reduction in arterial blood pressure. … Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension.

    Mixtures: CARDIOCAP A 80/5, CARDIOCAP A 80/5Categories: Agents Acting on the Renin-Angiotensin System
  3. Drug

    Indomethacin

    go.drugbank.com/drugs/DB00328
    ApprovedInvestigational

    Although deemed effective in reducing ocular inflammation in clinical studies, topical NSAIDs were also associated with a potential reduction in corneal sensitivity accompanied by an increased risk of … Intravenous indometacin is administered to close a hemodynamically significant patent ductus arteriosus, as indicated by clinical evidence, in premature infants.

    Products: Indomethacin ER
  4. Drug

    Nebivolol

    go.drugbank.com/drugs/DB04861
    ApprovedInvestigational

    [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than [atenolol], [propranolol], or [pindolol]. … [A182594] Nebivolol was granted FDA approval on 17 December 2007.[L7985]

    Mixtures: NEBIVOLOLO E IDROCLOROTIAZIDE EG, NEBIVOLOLO E IDROCLOROTIAZIDE EGProducts: NEBIVOLOLO EG, NEBIVOLOLO E IDROCLOROTIAZIDE ACCORD
  5. Drug

    Capsaicin

    go.drugbank.com/drugs/DB06774
    ApprovedInvestigational

    Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. … Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements

    Synonyms: (E)-8-Methyl-N-vanillyl-6-nonenamide, trans-8-Methyl-N-vanillyl-6-nonenamideMixtures: Medi-derm / L With Lidocaine, Doloracin/l Rx With Lidocaine
  6. Drug

    Febuxostat

    go.drugbank.com/drugs/DB04854
    ApprovedInvestigational

    [A230548] In February 2019, a black box warning for febuxostat was added, based on the findings of a post-market clinical study (the CARES trial) where there was an increased risk of cardiovascular … [L32238] Gout is a form of arthritis that is caused by the accumulation of uric acid crystal in or around a joint, leading to inflammation and further deposition of uric acid crystal deposition in bones

    Products: FEBUXOSTAT EG, FEBUXOSTAT AL 80MG FTA
  7. Drug

    Phenytoin

    go.drugbank.com/drugs/DB00252
    ApprovedInvestigationalVet approved

    Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants. … [A189219,A35884] Both parenteral and oral formulations of phenytoin are available on the market.[A189219]

    Categories: UGT1A1 Substrates with a Narrow Therapeutic Index, UGT1A6 Substrates with a Narrow Therapeutic IndexProducts: Phenytoin ER
  8. Drug

    Sodium fluoride

    go.drugbank.com/drugs/DB09325
    ApprovedInvestigational

    Now, sodium fluoride may be found in a variety of gels, varnishes, rinses, toothpaste products, and fluoride treatments provided in dental care. … Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as [Fluoride ion F-18].

    Mixtures: PREVENT 2 EN 1, E-Z CupsCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    Captopril

    go.drugbank.com/drugs/DB01197
    ApprovedInvestigational

    ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension. … Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).

    Synonyms: L-Captopril, D-2-methyl-3-mercaptopropanoyl-L-prolineMixtures: CAPTOPRIL HCT AL 50/25, CAPTOPRIL E IDROCLOROTIAZIDE HEXAL
  10. Drug

    Leuprolide

    go.drugbank.com/drugs/DB00007
    ApprovedInvestigational

    [A203126, A203132] Leuprolide was first approved in 1985 as a daily subcutaneous injection under the tradename Lupron™ by Abbvie Endocrine Inc. … Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH).

    Products: ELIGARD 22.5 MG ENJ. COZ. ICIN S.C. TOZ ICEREN SIRINGA VE COZUCU ICEREN SIRINGA, 1 ADET, LUPRON ® DEPOT 11.25 MG POLVO LIOFILIOZADO PARA RECONSTITUIR A SUSPENSIÓN INYECTABLE