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Bevacizumab
go.drugbank.com/drugs/DB00112ApprovedInvestigational[A192834,A192888,A192837,A192891,A192894] Bevacizumab is a humanized monoclonal IgG antibody that inhibits angiogenesis by binding and neutralizing VEGF-A. … There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.
Synonyms: Bei Fa Zhu DankangProducts: ZİRABEV 100 MG/4 ML İNFÜZYONLUK ÇÖZELTİ, 1 ADET, ZIRABEV CONCENTRATE FOR SOLUTION FOR INFUSION 100 MG/4 MLMirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigationalMirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepineClotrimazole
go.drugbank.com/drugs/DB00257ApprovedInvestigationalVet approvedThis drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s [A174094]. … As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094].
Mixtures: Imazol duo 10 mg/g + 2,5 mg/g Creme, SAEROGENTA-A CREAMCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersLarotrectinib
go.drugbank.com/drugs/DB14723ApprovedInvestigationalOn April 10, 2025, the FDA granted full drug approval.[L52805] … Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: VITRAKVI 100 MG SERT KAPSÜL, 56 ADET, VITRAKVI 20 MG/ML ORAL ÇÖZELTİ, 2x50 MLCalcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalCalcitriol plays a role in plasma calcium regulation in concert with parathyroid hormone (PTH) by enhancing absorption of dietary calcium and phosphate from the gastrointestinal tract, promoting renal … calcitriol has been demonstrated to increase energy efficiency by suppressing UCP2 expression, which is modulated by signaling pathways of classical nuclear receptors (nVDR), where calcitriol acts as a
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: K-LAM, QALYVİZ 0.5 MCG YUMUŞAK KAPSÜL, 100 ADETFludeoxyglucose (18F)
go.drugbank.com/drugs/DB09502ApprovedInvestigationalFludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with
Categories: Compounds used in a research, industrial, or household settingProducts: [18F] Fludeoxyglucose UJV 100 – 1500 MBq/ml Injektionslösung, Efdege 1,0 GBq/ml - InjektionslösungAbacavir
go.drugbank.com/drugs/DB01048ApprovedInvestigationalAbacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. … Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring.
Mixtures: TRIUMEQ® 50 MG / 600 MG / 300 MG, TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,90 FILM KAPLI TABLETProducts: ZIAGEN ORAL SOLÜSYON 300 MG/15 ML, 240 ML, ABACAVIRSOLUCION ORAL 20 MG/MLOndansetron
go.drugbank.com/drugs/DB00904ApprovedInvestigationalWithdrawn[L5221] The FDA withdrew its approval for the use of all intravenous drug products containing more than 16 mg of ondansetron hydrochloride in a single dose, due to a high risk of QT prolongation. … A competitive serotonin type 3 receptor antagonist.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: ONZYD 4 MG AGIZDA DAGILAN 10 TABLET, ONZYD 8 MG AGIZDA DAGILAN 10 TABLETTenoxicam
go.drugbank.com/drugs/DB00469ApprovedInvestigationalTenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: OKSAMEN-L 20 MG IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ (1 FLAKON, 1 AMPUL), TILCOTIL 20 MG 10 SUPPFerrous sulfate anhydrous
go.drugbank.com/drugs/DB13257ApprovedInvestigationalIron deficiency anemia is a large public health concern worldwide, especially in young children, infants, and women of childbearing age. … [A190528] Ferrous sulfate is a synthetic agent used in the treatment of iron deficiency. It is the gold standard of oral iron therapy in the UK and many other countries.[L2234,L2246]
Mixtures: Ferrograd - Fol 105 mg / 0,35 mg Filmtabletten, GYNOTARDYFERON 80 MG/0,35 MG UZATILMIŞ SALIMLI KAPLI TABLET, 30 ADETProducts: Ferro - Gradumet 105 mg Filmtabletten, FerrumAcino 100 mg magensaftresistente Hartkapseln