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Displaying results 5601 - 5610 of 10000 in total
  1. Drug

    Mesmulogene ancovacivec

    go.drugbank.com/drugs/DB06584
    Investigational

    with MVA-MUC1-IL2 vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) responses against tumor cells expressing MUC1, a tumor associated antigen, resulting in … Expression of IL-2 augments the specific CTL response against MUC1 expressing cells. [L5191]

  2. Drug

    Pelitinib

    go.drugbank.com/drugs/DB05524
    Investigational

    Pelitinib (EKB-569) is a potent, low molecular weight, selective, and irreversible inhibitor of epidermal growth factor receptor (EGFR) that is being developed as an anticancer agent.

    Synonyms: (2E)-N-(4-((3-chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxy-6-quinolinyl)-4-(dimethylamino)-2-butenamide
  3. Drug

    Prolease-r-hFSH

    go.drugbank.com/drugs/DB05826
    Experimental

    It provides patients with long term therapeutic benefit from a single administration rather than multiple injections. … Prolease-r-hFSH is a recombinant human follicle stimulating hormone (r-hFSH) with Alkermes' ProLease injectable sustained release drug delivery technology.

  4. Drug

    Saredutant

    go.drugbank.com/drugs/DB06660
    Investigational

    Saredutant (SR 48968) is a neurokinin-2 antagonist drug being developed as an antidepressant and anxiolytic by Sanofi-Aventis.

  5. Drug

    Apronalide

    go.drugbank.com/drugs/DB13221
    Approved

    Apronalide is approved in Japan. Apronalide has been withdrawn from the market in many other countries due to patient development of thrombocytopenic purpura [A174814].

  6. Drug

    Ferrous bisglycinate

    go.drugbank.com/drugs/DB11210
    Approved

    It is found in foods for food enrichment or in supplements for the treatment of iron deficiency or iron deficiency anemia. … Ferrous bisglycinate is a chelate that is used as a source of dietary iron.

  7. Drug

    Polydatin

    go.drugbank.com/drugs/DB11263
    Approved

    While it is isolated from the bark of *Picea sitchensis* or *Polygonum cuspidatum*, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products … It is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis [A27229].

  8. Drug

    Eldelumab

    go.drugbank.com/drugs/DB06116
    Investigational

    MDX-1100, a fully human antibody that targets IP10 (also known as CXCL10), a chemokine expressed in association with multiple inflammatory disease indications, such as rheumatoid arthritis, inflammatory

  9. Drug

    (+)-Mefloquine

    go.drugbank.com/drugs/DB05636
    Investigational

    (+)-Mefloquine was under investigation in clinical trial NCT00931697 (Study to Investigate the Safety, Tolerability and Pharmacokinetics of AD 452 [(+)-Mefloquine] Compared With Racemic Mefloquine) to … compare the efficacy of (+) Mefloquine vs. racemic [Mefloquine].

  10. Drug

    Roquinimex

    go.drugbank.com/drugs/DB11366
    Experimental

    Additionally, roquinimex is known to inhibit angiogenesis and to decrease the synthesis of TNF alpha. … Roquinimex is a derivative of quinoline that presents immunostimulant properties. Its effects are suggested to increase the activity of NK cells and macrophage cytotoxicity.