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ABBV-706
go.drugbank.com/drugs/DB18710InvestigationalABBV-706 is an antibody-drug conjugate that is anti-SEZ6.[L49156,L49161]
GSK-239512
go.drugbank.com/drugs/DB15120InvestigationalGSK-239512 is under investigation in clinical trial NCT00474513 (An Imaging Study to Investigate the Distribution of GSK239512 in the Brain.).
Fosmanogepix
go.drugbank.com/drugs/DB15183InvestigationalFosmanogepix is under investigation in clinical trial NCT03604705 (An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia).
AMB-301
go.drugbank.com/drugs/DB18094ExperimentalAMB-301 is an AAV gene therapy delivering E-selectin.[L48101] It is under investigation for the treatment of Buerger disease.
Galactose-uridine-5'-diphosphate
go.drugbank.com/drugs/DB03501ExperimentalServes as a source of galactose in the synthesis of lipopolysaccharides, cerebrosides, and lactose. … A nucleoside diphosphate sugar which can be epimerized into UDPglucose for entry into the mainstream of carbohydrate metabolism.
Bentoquatam
go.drugbank.com/drugs/DB00516ApprovedBentoquatam contains bentonite, a clay, and is only effective as long as the film is visible on the skin. … Bentoquatam is a topical medication intended to act as a shield against exposure to the irritating substance urushiol, found in plants such as poison ivy or poison oak.
NOX-700
go.drugbank.com/drugs/DB05464ExperimentalNOX-700, an new orally active dithiocarbamate-based nitric oxide (NO) blocking agent that is in development for the treatment of diabetes mellitus (type 2 diabetes). … In animal studies, NOX-700 lowered serum glucose, improved glucose tolerance, and reduced the percentage of total glycated hemoglobin.
Ispectamab debotansine
go.drugbank.com/drugs/DB18456InvestigationalIspectamab debotansine is an antibody drug conjugate comprised of an anti-B cell maturation (BCMA) IgG1 humanized antibody conjugated covalently to the dibenzocyclooctyne (DBCO) noncleavable linker maytansinoid
Prinaberel
go.drugbank.com/drugs/DB06832InvestigationalPrinaberel is an estrogen receptor beta agonist.
Glypromate
go.drugbank.com/drugs/DB05633ExperimentalIn December 2008, the company discontinued further development of the drug after it failed to show an observable effect. … glycine-proline glutamate), a naturally occurring small-molecule neuroprotectant derived from IGF-1 which inhibits caspase III dependent apoptosis, for the potential treatment of neurodegenerative diseases by IV