NAV

Bentoquatam

Identification

Name
Bentoquatam
Accession Number
DB00516
Description

Bentoquatam is a topical medication intended to act as a shield against exposure to the irritating substance urushiol, found in plants such as poison ivy or poison oak. Bentoquatam contains bentonite, a clay, and is only effective as long as the film is visible on the skin.

Type
Small Molecule
Groups
Approved
Synonyms
  • Bentoquatam

Pharmacology

Pharmacology
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Indication

Used to prevent or reduce the severity of allergic contact dermatitis due to urushiol, the allergenic resin of poison ivy, poison oak, and poison sumac.

Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Bentoquatam protects the skin like a shield against poison ivy, poison oak, and poison sumac by physically blocking skin contact with their resin. The best protection against getting these conditions is to avoid contact with these plants. This medicine does not dry oozing and weeping caused by the rash of poison ivy, poison oak, or poison sumac.

Mechanism of action

The mechanism of action is unknown. It is thought topically applied bentoquatam acts as a physical barrier that interferes with the adsorption of antigens onto the skin and reduces absorption of antigens into the skin. It probably does not work by modifying the systemic allergic response.

Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
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Toxicity

Rare side effects include mild erythema (mild redness of skin).

Affected organisms
  • Humans and other mammals
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
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CarbamazepineBentoquatam can cause a decrease in the absorption of Carbamazepine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Chenodeoxycholic acidThe serum concentration of Chenodeoxycholic acid can be decreased when it is combined with Bentoquatam.
Cholic AcidThe serum concentration of Cholic Acid can be decreased when it is combined with Bentoquatam.
DeferasiroxBentoquatam can cause a decrease in the absorption of Deferasirox resulting in a reduced serum concentration and potentially a decrease in efficacy.
Dehydrocholic acidThe serum concentration of Dehydrocholic acid can be decreased when it is combined with Bentoquatam.
Deoxycholic acidThe serum concentration of Deoxycholic acid can be decreased when it is combined with Bentoquatam.
DolutegravirThe serum concentration of Dolutegravir can be decreased when it is combined with Bentoquatam.
EltrombopagBentoquatam can cause a decrease in the absorption of Eltrombopag resulting in a reduced serum concentration and potentially a decrease in efficacy.
HalofantrineBentoquatam can cause a decrease in the absorption of Halofantrine resulting in a reduced serum concentration and potentially a decrease in efficacy.
MephenytoinBentoquatam can cause a decrease in the absorption of Mephenytoin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Interactions
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Food Interactions
Not Available

Products

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International/Other Brands
IvyBlock (Hyland's)

Categories

Drug Categories
Classification
Not classified

Chemical Identifiers

UNII
7F465U79Q1
CAS number
1340-69-8
InChI Key
Not Available
InChI
Not Available
IUPAC Name
Not Available
SMILES
Not Available

References

General References
  1. Scott MJ, Heumann MA, DeBruyckere DM, Brundage TW, Kohn MA: The feasibility of using skin protectant products and education to prevent poison oak. Wilderness Environ Med. 2002 Fall;13(3):206-8. [PubMed:12353598]
Human Metabolome Database
HMDB14657
PubChem Substance
46508055
RxNav
134568
ChEMBL
CHEMBL1201446
PharmGKB
PA164748098
Drugs.com
Drugs.com Drug Page
Wikipedia
Bentonite
MSDS
Download (86.6 KB)

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
  • Standard homeopathic co
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
PropertyValueSource
water solubilitySolubleNot Available
Predicted Properties
Not Available
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on June 13, 2005 13:24 / Updated on March 04, 2021 11:14