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Blonanserin
go.drugbank.com/drugs/DB09223InvestigationalBlonanserin is an atypical antipsychotic approved in Japan in January, 2008.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTefidsogene civaparvovec
go.drugbank.com/drugs/DB16789InvestigationalTefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing. … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes
Pegaptanib
go.drugbank.com/drugs/DB04895ApprovedWithdrawnPegaptanib is a polynucleotide aptamer. Pegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and vessel permeability. Pegaptanib was granted FDA approval on 17 September 2004.
Tropisetron
go.drugbank.com/drugs/DB11699ApprovedInvestigationalWithdrawnTropisetron is an indole derivative with antiemetic activity. … As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesOportuzumab monatox
go.drugbank.com/drugs/DB05319InvestigationalVB4-845 is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells. … VB4-845 is a fusion protein containing humanized scFv specific for the epithelial cell adhesion molecule, Ep-CAM, a tumor cell-associated target highly expressed on carcinoma cells of epithelial origin
Sulfameter
go.drugbank.com/drugs/DB06821ApprovedLong acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseHexoprenaline
go.drugbank.com/drugs/DB08957ApprovedWithdrawnHexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent.
Categories: Adrenergics for Systemic Use, Drugs for Obstructive Airway DiseasesProducts: Gynipral 25 µg - Konzentrat zur InfusionsbereitungPagoclone
go.drugbank.com/drugs/DB04903InvestigationalPagoclone is an anxiolytic drug from the cyclopyrrolone family, which is related to other more well known drugs such as the sleeping medication zopiclone.
Eflapegrastim
go.drugbank.com/drugs/DB15001ApprovedInvestigationalThe primary factor associated with FN risk is the chemotherapy regimen being administered - regimens are classified as either high-, intermediate-, or low-risk for FN, and relevant guidelines recommend … [A252320] It typically develops during the first cycle of chemotherapy and is associated with an increased risk of morbidity and mortality.
Beta-(1,3)-D glucan
go.drugbank.com/drugs/DB16468InvestigationalSynonyms: PC-3 type glucanCategories: Experimental Unapproved Treatments for COVID-19