Search

Displaying results 5641 - 5650 of 10000 in total

Drug
AI-850
go.drugbank.com/drugs/DB05842
Experimental
AI-850 is a Cremophor(R)-free formulation of paclitaxel, the active ingredient in Taxol(R), a product used to treat a variety of solid tumors.
Drug
Satavaptan
go.drugbank.com/drugs/DB14923
Investigational
Satavaptan is under investigation in clinical trial NCT00359437 (Satavaptan in the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Liver).
Categories: Heterocyclic Compounds, 1-Ring
Drug
7,8-dihydrobiopterin
go.drugbank.com/drugs/DB04400
Experimental
7,8-Dihydrobiopterin is an inhibitor of the enzyme dihydroneopterin aldolase (DHNA), which catalyzes the conversion of 7,8-Dihydrobiopterin to 6-hydroxymethyl-7,8-dihydropterin and glycolaldehyde.
Categories: Heterocyclic Compounds, 2-RingSynonyms: L-erythro-q-Dihydrobiopterin, q-BH2
Drug
Metampicillin
go.drugbank.com/drugs/DB13836
Experimental
Metampicillin is a penicillin antibiotic prepared by the reaction of ampicillin with formaldehyde. It is hydrolysed in aqueous solution to form ampicillin. … Hydrolysis is rapid under acid conditions like the stomach.
Categories: Penicillin G, Heterocyclic Compounds, 2-Ring
Drug
INM004
go.drugbank.com/drugs/DB17791
Investigational
INM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being investigated to treat Shiga-toxin producing bacterial infection relating to the prevention of hemolytic
Synonyms: Anti-Shiga toxin hyperimmune equine immunoglobulin F(ab')2 fragment, Neutralizing equine anti-Stx hyperimmune immunoglobulin F(ab')2 fragment
Drug
Adecatumumab
go.drugbank.com/drugs/DB05006
Investigational
Adecatumumab is a recombinant human monoclonal antibody of the IgG1 subclass with a binding specificity to epithelial cell adhesion molecule (EpCAM). … EpCAM (CD326) is a cell surface protein that is frequently expressed at high level on most solid tumor types, including prostate, breast, colon, gastric, ovarian, pancreatic and lung cancer.
Drug
Kinetin
go.drugbank.com/drugs/DB11336
Approved
While kinetin is used in tissue cultures to produce new plants, it is also found in cosmetic products as an anti-aging agents. … Kinetin is a cytokinin which are plant hormones promotes cell division and plant growth. It was shown to naturally exist in DNA of organisms including humans and various plants.
Categories: Heterocyclic Compounds, 2-Ring
Drug
Ceftiofur
go.drugbank.com/drugs/DB11485
ExperimentalVet approved
It is resistant to hydrolysis by beta-lactamase, and has activity against both Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported. … It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product.
Categories: Heterocyclic Compounds, 2-Ring
Drug
Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine
go.drugbank.com/drugs/DB15813
Investigational
, modify artificial antigen presenting cells (aAPC), and activate T-cells. … Through analysis of potential immunogenic targets of the SARS-Cov2 genome, a synthetic ‘minigene’ was developed using domains of viral structural proteins and a polyprotein protease.
Drug
Foretinib
go.drugbank.com/drugs/DB12307
Investigational
Foretinib is an orally available small molecule compound designed to target multiple RTKs implicated in the development, progression and spread of cancer. … It inhibits the activation of MET, RON, ERK and AKT, decreased proliferation and increased apoptosis.
Categories: Heterocyclic Compounds, 2-Ring