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N-acetyl-beta-neuraminic acid
go.drugbank.com/drugs/DB04265ExperimentalAn N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
Wortmannin
go.drugbank.com/drugs/DB08059ExperimentalWortmannin is a steroid metabolite of _Penicillium funiculosum_ and _Talaromyces wortmannii_ fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).
Rheinanthrone
go.drugbank.com/drugs/DB13175ExperimentalIt is commonly produced by plants of the Rheum species [L772].
Ozekibart
go.drugbank.com/drugs/DB18675InvestigationalOzekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5). It is being investigated for the treatment of chondrosarcoma.
Imdusiran
go.drugbank.com/drugs/DB19014InvestigationalImdusiran is under investigation in clinical trial NCT06245291 (Study of Imdusiran (AB-729) in Combination With Intermittent Dosing of Durvalumab in Subjects With Chronic HBV Infection).
Synonyms: AB-729MK-8189
go.drugbank.com/drugs/DB19153InvestigationalMK-8189 is under investigation in clinical trial NCT04624243 (Efficacy and Safety of MK-8189 in Participants With an Acute Episode of Schizophrenia (MK-8189-008)).
Sabirnetug
go.drugbank.com/drugs/DB19438InvestigationalSabirnetug is under investigation in clinical trial NCT06335173 (A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants With Early Alzheimer's Disease (ALTITUDE-AD)).
Theanine
go.drugbank.com/drugs/DB12444InvestigationalTheanine, a precursor of ethylamine, is found in green tea. It is under investigation in clinical trial NCT00291070 (Effects of L-Theanine in Boys With ADHD).
Dubermatinib
go.drugbank.com/drugs/DB15187InvestigationalDubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL).
Buntanetap
go.drugbank.com/drugs/DB15317InvestigationalBuntanetap (previously known as Posiphen) is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease).