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Displaying results 5651 - 5660 of 9322 in total
  1. Drug

    Linsitinib

    go.drugbank.com/drugs/DB06075
    Investigational

    IGF-1R inhibitor OSI-906 selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. … An orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity.

  2. Drug

    Canfosfamide

    go.drugbank.com/drugs/DB04972
    Investigational

    Canfosfamide is an active agent in chemotherapy-resistant ovarian cancer.

  3. Drug

    Tymazoline

    go.drugbank.com/drugs/DB08803
    Experimental

    Tymazoline is a nasal preparation.

  4. Drug

    Tosatoxumab

    go.drugbank.com/drugs/DB16557
    Investigational

    by protecting against destruction of host cells mediated by the toxin. … Tosatoxumab is a fully-human monoclonal antibody (IgG1λ) targeting the Staphylococcus aureus alpha-toxin or the S. aureus alpha-hemolysin[A191829, L31568, L31573] and thereby preserving human immune cells

  5. Drug

    Tifuvirtide

    go.drugbank.com/drugs/DB05413
    Investigational

    Tifuvirtide is the first members of a new class of anti-HIV drugs which is also called fusion inhibitors. It has received fast-track designation from the FDA and is in Phase I/II clinical testing.

  6. Drug

    ABT-510

    go.drugbank.com/drugs/DB05434
    Investigational

    It is developed by Abbott Laboratories for the treatment of Solid Tumors, Lymphoma and Melanoma.

  7. Drug

    BHV-1310

    go.drugbank.com/drugs/DB22674
    Experimental

    BHV-1310 is a IgG<sub>1,2,4</sub> selective degrader being investigated for the treatment of Grave's disease.

  8. Drug

    Benzoylecgonine

    go.drugbank.com/drugs/DB01515
    ExperimentalIllicit

    It is the main pharmaceutical ingredient in the investigational drug Esterom, a topical solution used for the relief of muscle pain that is not FDA approved or on the market in the United States. … It is excreted in the urine of cocaine users after processing in the liver.

  9. Drug

    Platelet Lysate

    go.drugbank.com/drugs/DB15869
    Investigational

    Platelet lysate is an acellular compound composed of platelet proteins while also being void of cellular debris, thus making the lysate rich with growth factors. … [A220188] It is extracted through lysis of the plasma membrane of platelets. Because white cell antigens are low in prepared lysate, there is a minimized likelihood of immune responses.

  10. Drug

    Surabgene lomparvovec

    go.drugbank.com/drugs/DB21780
    Investigational

    Surabgene Lomparvovec is under investigation in clinical trial NCT07007065 (Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity