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Displaying results 5671 - 5680 of 10000 in total
  1. Drug

    Amediplase

    go.drugbank.com/drugs/DB06679
    Experimental

    Amediplase is a recombinant chimeric plasminogen activator, consisting of the kringle 2 domain from the A-chain of tissue plasminogen activator (t-PA) and the carboxy terminal region of pro-urokinase.

  2. Drug

    Tofisopam

    go.drugbank.com/drugs/DB08811
    Investigational

    The D-enantiomer ([dextofisopam]) is currently in phase II trials in the U.S. for the treatment of irritable bowel syndrome. … Tofisopam (marketed under brand names Emandaxin and Grandaxin) is a 2,3-benzodiazepine drug which is a benzodiazepine derivative.

  3. Drug

    Mupadolimab

    go.drugbank.com/drugs/DB16488
    Investigational

    CPI-006 was investigated in clinical trials NCT03454451, NCT04464395, and NCT04734873 to evaluate its safety and efficacy. … NCT03454451 focused on advanced cancers (e.g., non-small cell lung cancer, renal cell cancer, colorectal cancer).

  4. Drug

    Carmofur

    go.drugbank.com/drugs/DB09010
    ApprovedWithdrawn

    Carmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.

  5. Drug

    ATL-104

    go.drugbank.com/drugs/DB05670
    Investigational

    ATL-104 is a potent mitogen for epithelial cells of the gastrointestinal tract. In animal models, ATL-104 aids regeneration of the gastrointestinal tract after treatment with chemotherapeutic agents.

  6. Drug

    AZD2315

    go.drugbank.com/drugs/DB06540
    Experimental

    The drug AZD2315, an immunosuppressant developed by AstraZeneca, was in Phase 1 clinical trials for the treatment of rheumatoid arthritis but was discontinued during this phase

    Synonyms: L-ALANINAMIDE, N-(1-OXO-5-PHENYLPENTYL)-L-ALANYL-L-ARGINYL-L-ALANYL-(.ALPHA.S,3R)-3-AMINO-.ALPHA.-METHYL-2-OXO-1-PYRROLIDINEACETYL-L-ALANYL-L-ARGINYL-N-(4-(2-AMINO-2-OXOETHYL)PHENYL)-, ACETATE (1:2), L-ALANINAMIDE, N-(1-OXO-5-PHENYLPENTYL)-L-ALANYL-L-ARGINYL-L-ALANYL-(.ALPHA.S,3R)-3-AMINO-.ALPHA.-METHYL-2-OXO-1-PYRROLIDINEACETYL-L-ALANYL-L-ARGINYL-N-(4-(2-AMINO-2-OXOETHYL)PHENYL)-, DIACETATE
  7. Drug

    Lavamilast

    go.drugbank.com/drugs/DB19767
    Experimental

    Lavamilast has a monoisotopic molecular weight of 520.16 Da. … Lavamilast is a small molecule drug. The usage of the INN stem '-milast' in the name indicates that Lavamilast is a Phosphodiesterase-4 (PDE4) inhibitor.

  8. Drug

    Itacnosertib

    go.drugbank.com/drugs/DB21463
    Experimental

    Itacnosertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Itacnosertib is a serine/threonine kinase inhibitor. … Itacnosertib has a monoisotopic molecular weight of 468.24 Da.

  9. Drug

    Cotosudil

    go.drugbank.com/drugs/DB21482
    Experimental

    Cotosudil is a small molecule drug. The usage of the INN stem '-sudil' in the name indicates that Cotosudil is a Rho protein kinase inhibitor. … Cotosudil has a monoisotopic molecular weight of 319.14 Da.

  10. Drug

    Firzacorvir

    go.drugbank.com/drugs/DB21494
    Experimental

    Firzacorvir is a small molecule drug. The usage of the INN stem '-corvir' in the name indicates that Firzacorvir is a core protein (Cp) inhibitor. … Firzacorvir has a monoisotopic molecular weight of 484.06 Da.