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Displaying results 5681 - 5690 of 10000 in total
  1. Drug

    Relebactam

    go.drugbank.com/drugs/DB12377
    ApprovedInvestigational

    [A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. … Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to [avibactam].

    Categories: MATE 1 Substrates, MATE 2 Substrates
  2. Drug

    Anagliptin

    go.drugbank.com/drugs/DB12417
    Investigational

    Anagliptin is under investigation for the treatment of LDL Cholesterol, Coronary Disease, Diabetes Mellitus, Glycosylated Hemoglobin, and Dipeptidyl-Peptidase 4 Inhibitors.

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    HSD-016

    go.drugbank.com/drugs/DB12419
    Investigational

    Hsd 016 is under investigation in clinical trial NCT00838461 (Study Evaluating the Safety, Pharmacokinetics (PK), and Pharmacodynamices (PD) of HSD-016).

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Muplestim

    go.drugbank.com/drugs/DB12431
    Investigational

    Muplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL … -3) in HIV Infected Patients With Cytopenia).

    Categories: Interleukin-3Synonyms: Interleukin 3, Interleukin-3
  5. Drug

    Lynestrenol

    go.drugbank.com/drugs/DB12474
    ApprovedWithdrawn

    Lynestrenol is a progestin and prodrug of [norethisterone].

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ORGAMETRÄ°L 5 MG TABLET, 30 ADET
  6. Drug

    Pimonidazole

    go.drugbank.com/drugs/DB12485
    Investigational

    Pimonidazole is under investigation for the diagnostic of Prostate Cancer and Head and Neck Cancer.

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Inebilizumab

    go.drugbank.com/drugs/DB12530
    ApprovedInvestigational

    [A214283, A214286] Inebilizumab is a humanized afucosylated monoclonal IgG1 antibody directed against the broadly expressed B-cell surface antigen CD19. … Inappropriate growth of or self-directed antibody production by B-cells is the etiological underpinning of a variety of conditions, including the multiple sclerosis-like neurological condition neuromyelitis

    Products: UPLIZNA®
  8. Drug

    Navicixizumab

    go.drugbank.com/drugs/DB12634
    Investigational

    Navicixizumab is under investigation in clinical trial NCT02298387 (A Phase 1 Study of Navicixizumab in Subjects With Solid Tumors).

  9. Drug

    JNJ-42396302

    go.drugbank.com/drugs/DB12657
    Investigational

    Jnj 42396302 is under investigation in clinical trial NCT01732237 (A Study to Investigate the Pharmacokinetics of JNJ-42396302, JNJ-53773187 and JNJ-42692507 in Healthy Male Participants).

  10. Drug

    Aviscumine

    go.drugbank.com/drugs/DB12684
    Investigational

    Cy 503 is under investigation in clinical trial NCT00658437 (Aviscumine for the Treatment of Malignant Melanoma Stage IV After Failure of Prior Therapy).

    Categories: N-Glycosyl Hydrolases