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Indomethacin
go.drugbank.com/drugs/DB00328ApprovedInvestigationalAlthough deemed effective in reducing ocular inflammation in clinical studies, topical NSAIDs were also associated with a potential reduction in corneal sensitivity accompanied by an increased risk of … Indometacin was first discovered in 1963 and it was first approved for use in the U.S. by the Food and Drug Administration in 1965, [A486] along with other acetic acid derivatives such as [diclofenac]
Products: Indomethacin ERNebivolol
go.drugbank.com/drugs/DB04861ApprovedInvestigational[A182594] Nebivolol was granted FDA approval on 17 December 2007.[L7985] … [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than [atenolol], [propranolol], or [pindolol].
Mixtures: NEBIVOLOLO E IDROCLOROTIAZIDE EG, NEBIVOLOLO E IDROCLOROTIAZIDE EGProducts: NEBIVOLOLO EG, NEBIVOLOLO E IDROCLOROTIAZIDE ACCORDTriclosan
go.drugbank.com/drugs/DB08604ApprovedIt is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards … An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group.
Mixtures: PREVENT 2 EN 1, T-Chem E2 RatedProducts: Antibacterial Spray Hand Soap/savon Antibacterien En Aerosol Pour Les Mains, Ben E. Keith Foaming Antibacterial Hand CleanerRopinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalIn 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547]. … Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease.
Products: ROPINIROLO EG, ROPINIROLO EG STADACapsaicin
go.drugbank.com/drugs/DB06774ApprovedInvestigationalCapsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements … Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations.
Mixtures: NuDroxiPAK E-400, Trubrexa Patch ERSynonyms: (E)-8-Methyl-N-vanillyl-6-nonenamide, trans-8-Methyl-N-vanillyl-6-nonenamideCitalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigational[A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 years or older.[L5230] … Citalopram is an antidepressant belonging to the class of selective _serotonin-reuptake inhibitors_ (SSRIs) widely used to treat the symptoms of depression.
Products: CITALOPRAM EG, CITALOPRAM EG STADALansoprazole
go.drugbank.com/drugs/DB00448ApprovedInvestigational[A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD)
Products: LANSOPRAZOLO EG, LANSOPRAZOLO EG STADAFebuxostat
go.drugbank.com/drugs/DB04854ApprovedInvestigational[A39743] In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. … (CV) fatal outcomes in patients with gout and known cardiovascular disease treated with febuxostat, when compared to those treated with allopurinol.
Products: FEBUXOSTAT EGTriamcinolone
go.drugbank.com/drugs/DB00620ApprovedInvestigationalVet approved[L8246,L8249,L8252,L8255,L8258,L8261,L8264] Triamcinolone was granted FDA approval on 3 December 1957. … [L8249] Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and triamcinolone diacetate.
Mixtures: Hydroquinone 6% / Tretinoin 0.05% / Triamcinolone 0.025%, Hydroquinone 4% / Tretinoin 0.025% / Triamcinolone Acetonide 0.025%Products: VOLONIMAT SALBE N, KENALOG IN ORABASELacosamide
go.drugbank.com/drugs/DB06218ApprovedInvestigational[A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved by the FDA in October 2008. … [A262681] It was granted approval by Health Canada in September 2010.[L49206]
Synonyms: (R)-2-acetamido-N-benzyl-3- methoxypropionamide, (+)-(2R)-2-(ACETYLAMINO)-N-BENZYL-3-METHOXYPROPANAMIDEProducts: LACOSAMIDE EG, LASOMID IN