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Displaying results 561 - 570 of 10000 in total
  1. Drug

    Moxonidine

    go.drugbank.com/drugs/DB09242
    ApprovedInvestigationalWithdrawn

    As well, moxonidine has been shown to present blood pressure-independent beneficial effects on insulin resistance syndrome. … It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive.

    Products: MOXONIDINA EG
  2. Drug

    Terbinafine

    go.drugbank.com/drugs/DB00857
    ApprovedInvestigationalVet approved

    [A1279,A1281,L9068] Terbinafine hydrochloride was granted FDA approval on 30 December 1992.[L9064] … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues.

    Synonyms: (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine, (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamineProducts: TERBINAFINA EG, PMS-terbinafine
  3. Drug

    Tranexamic acid

    go.drugbank.com/drugs/DB00302
    ApprovedInvestigational

    [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986.[L31858] … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding.

    Products: ACIDO TRANEXAMICO EG, TRANSAMINE 50 MG/ML IV ENJ COZELTI, 5 ML
  4. Drug

    Penciclovir

    go.drugbank.com/drugs/DB00299
    Approved

    Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.

    Products: EX-LOVIR % 1 KREM 2 G
  5. Drug

    Atosiban

    go.drugbank.com/drugs/DB09059
    ApprovedInvestigational

    Atobisan was developed by the Swedish company Ferring Pharmaceuticals. It was first reported in the literature in 1985. … Although initial studies suggested it could be used as a nasal spray and hence would not require hospital admission, it is not used in that form.

    Products: GBM-PIS, Atosiban Accord 6,75 mg/0,9 ml Injektionslösung in einer Fertigspritze
  6. Drug

    Aceclofenac

    go.drugbank.com/drugs/DB06736
    Approved

    In 1991, aceclofenac was developed as an analog of a commonly prescribed NSAID, [DB00586], via chemical modification in effort to improve the gastrointestinal tolerability of the drug. … Aceclofenac is also reported to be effective in other painful conditions such as dental and gynaecological conditions [A19672].

    Products: ACECLOFENAC EG
  7. Drug

    Theophylline

    go.drugbank.com/drugs/DB00277
    ApprovedInvestigational

    Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. … Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for asthma, bronchospasm, and COPD.

    Mixtures: Theophylline in Dextrose, Theophylline in DextroseProducts: PMS-theophylline Elixir, Theo ER
  8. Drug

    Methotrimeprazine

    go.drugbank.com/drugs/DB01403
    Approved

    (From Martindale, The Extra Pharmacopoeia, 30th ed, p604) … It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine.

    Synonyms: (-)-(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amineProducts: PMS-methotrimeprazine
  9. Drug

    Cefepime

    go.drugbank.com/drugs/DB01413
    ApprovedInvestigational

    Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. … Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.

    Synonyms: (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylateProducts: Maxipime for Injection-pws IV 2gm, Maxipime for Injection -pws IV Im 1g
  10. Drug

    Zolmitriptan

    go.drugbank.com/drugs/DB00315
    ApprovedInvestigational

    [A193797] Zolmitriptan was first approved by the FDA for sale by Zeneca Pharmaceuticals under the trade name Zomig® on November 25, 1997. … [A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and lipophilicity.

    Products: PMS-zolmitriptan, PMS-zolmitriptan ODT