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Displaying results 561 - 570 of 10000 in total
  1. Drug

    Botaretigene sparoparvovec

    go.drugbank.com/drugs/DB16814
    Investigational

    Synonyms: VIRUS 5 VECTOR AAV-RPGR HUMAN RHODOPSIN KINASE PROMOTER FRAGMENT-REGULATED HUMAN RETINITIS PIGMENTOSA GTPASE REGULATOR RPGR-ORF15 ISOFORM GENE VARIANT PLUS ADENO-ASSOCIATED VIRUS 2 INVERTED TERMINAL REPEAT
  2. Drug

    Ticagrelor

    go.drugbank.com/drugs/DB08816
    ApprovedInvestigational

    [A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y<sub>12</sub> receptor antagonism.[A2903] Unlike [clopidogrel], ticagrelor is not a prodrug. … [A2903] It is marketed by Astra Zeneca as Brilinta in the US[L14201] and Brilique or Possia in the EU,[L14207]. Ticagrelor was granted EMA approval on 3 December 2010.

    Categories: Purinergic P2 Receptor Antagonists, Purinergic P2Y Receptor AntagonistsProducts: Ag-ticagrelor
  3. Drug

    VEGFR 2 Kinase inhibitor I

    go.drugbank.com/drugs/DB17061
    Experimental

    Synonyms: Vegf receptor 2 kinase inhibitor i
  4. Drug

    Beludavimab

    go.drugbank.com/drugs/DB18952
    Investigational

    Beludavimab is under investigation in clinical trial NCT04746183 (AGILE (Early Phase Platform Trial for COVID-19)).

    Synonyms: IMMUNOGLOBULIN G1 (246-ALANINE,340-LEUCINE,342-GLUTAMIC ACID,438-LEUCINE,444-SERINE), ANTI-(SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 SPIKE GLYCOPROTEIN RECEPTOR-BINDING DOMAIN) (HUMAN MONOCLONAL
  5. Drug

    Ascorbic acid

    go.drugbank.com/drugs/DB00126
    ApprovedInvestigationalNutraceutical

    Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant. … A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables.

    Mixtures: Eden With Vitamins A, C, and E, Aces Formula/formule A A SCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Tadalafil

    go.drugbank.com/drugs/DB00820
    ApprovedInvestigational

    In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and a longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment … Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.

    Products: N/a, Ag-tadalafil
  7. Drug

    Ersodetug

    go.drugbank.com/drugs/DB18182
    Investigational

    Synonyms: immunoglobulin G2-kappa, anti-[Homo sapiens INSR (insulin receptor)], Homo sapiens monoclonal antibody, allosteric, Immunoglobulin G2, anti-(human insulin receptor) (human monoclonal RZ358 γ2-chain), disulfide with human monoclonal RZ358 κ-chain, dimer
  8. Drug

    Firolimogene autotemcel

    go.drugbank.com/drugs/DB18147
    Experimental

    Synonyms: AUTOLOGOUS CD34+ CELLS ISOLATED FROM BONE MARROW OF NEWLY DIAGNOSED X-LINKED SEVERE COMBINED IMMUNODEFICIENCY (X-SCID) PATIENTS, TRANSDUCED EX VIVO WITH A SELF-INACTIVATING LENTIVIRAL VECTOR, ENCODING, CODON-OPTIMIZED HUMAN INTERLEUKIN-2 RECEPTOR SUBUNIT
  9. Drug

    Equecabtagene autoleucel

    go.drugbank.com/drugs/DB19016
    Investigational

    Synonyms: autologous T lymphocytes obtained from peripheral blood mononuclear cells by leukapheresis, transduced with a self-inactivating, non-replicating lentiviral vector encoding a chimeric antigen receptor (
  10. Drug

    Plutavimab

    go.drugbank.com/drugs/DB18856
    Investigational

    Plutavimab is under investigation in clinical trial NCT04900428 (Study to Evaluate a Single Intranasal Dose of STI-2099 (COVI-DROPS™) in Outpatient Adults With COVID-19 (UK)).

    Synonyms: Immunoglobulin g1 (234-alanine,235-alanine), anti-(severe acute respiratory syndrome coronavirus 2 spike glycoprotein receptor-binding domain) (human monoclonal sti-2020 .gamma.1-chain), disulfide with