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Omega-3-acid ethyl esters
go.drugbank.com/drugs/DB09539ApprovedInvestigationalmg/dL) hypertriglyceridemia[FDA Label][A176687]. … that contain eicosapentaenoic acid-ethyl ester (EPA) and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500
Mixtures: Mi-Omega NFProducts: OMACOR 1000 mg Weichkapseln, Zodin 1000 mg - WeichkapselnCorifollitropin alfa
go.drugbank.com/drugs/DB09066ApprovedInvestigationalMultiple studies and a meta-analysis suggest that corifollitropin alfa is as efficacious as recombinant FSH in terms of live birth rate, ongoing pregnancy rate, as well as clinical pregnancy rate. … Corifollitropin alfa is marketed as Elonva in more than 75 countries [L2272]. Corifollitropin alfa is produced by a method known as ‘recombinant DNA technology’.
Products: ELONVA 150 MCG/0,5 ML ENJEKSIYONLUK COZELTI, 1 ADET, ELONVA 150 MCG/0,5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADETMilnacipran
go.drugbank.com/drugs/DB04896ApprovedInvestigational-1 (BACE-1), which has investigationally been associated with β-amyloid plaque formation - making the agent a possible course of treatment for Alzheimer's disease [A175957]. … Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) and like many agents in this category was originally developed for and continues to be approved and indicated for the treatment
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: IXEL 50 MG KAPSUL, 56 ADET, Ixel 50 mg - KapselnLatanoprost
go.drugbank.com/drugs/DB00654ApprovedInvestigational[A184493] It has been found to be well-tolerated and its use does not normally result in systemic adverse effects like other drugs used to treat elevated intraocular pressure, such as [Timolol]. … It was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment.
Synonyms: propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate, isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoateMixtures: Xalacom 50 Mikrogramm/ml + 5 mg/ml Augentropfen, LatanoTim-Vision 50 Mikrogramm/ml + 5 mg/ml AugentropfenSebelipase alfa
go.drugbank.com/drugs/DB11563ApprovedInvestigationalIt was first approved by both the FDA and EMA in 2015 and is marketed under the brand name Kanuma (Alexion Pharmaceuticals).[L39337,L39342]
Synonyms: SBC-102Products: KANUMA® 2 MG/ML CONCENTRADO PARA SOLUCION PARA INFUSION.Iloprost
go.drugbank.com/drugs/DB01088ApprovedInvestigational[A263326] Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately 53:47.[L50146] It is a potent vasodilator with reported anti-thrombotic properties. … [A263316] Iloprost is available as an inhaled solution and intravenous formulations. It is used to treat pulmonary arterial hypertension (PAH) [L50146] and frostbites.[L50151]
Synonyms: (5E)-[3aS,4R,5R,6aS)-5-Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen-2(1H)-ylidene]pentanoic acid, PENTANOIC ACID, 5-((3AS,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-((1E,3S)-3-HYDROXY-4-METHYL-1-OCTEN-6-YNYL)-2(1H)-PENTALENYLIDENE)-, (5E)-Products: VENTAVIS 10 MCG/ML NEBULIZATOR ICIN SOLUSYON ICEREN AMPUL, 100 ADET, Ilomedin 50 µg/0,5 ml - InfusionslösungskonzentratBosutinib
go.drugbank.com/drugs/DB06616ApprovedInvestigational[A6902,A261796,A261801] The first BCR-ABL inhibitor, [imatinib], was introduced over a decade ago as a breakthrough in CML management; however, emerging resistance to [imatinib] poses challenges in achieving … This approval was based on favorable results obtained from the open-label, randomized, multicenter trial BFORE that showed a significant improvement in major molecular response, defined as a ≤0.1% BCR
Synonyms: 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrileCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsIpratropium
go.drugbank.com/drugs/DB00332ApprovedInvestigational] was approved in 1996. … [A176957] Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy product was FDA approved in 1986, while the combination product of ipratropium and [albuterol
Mixtures: İPRAVENT 20 MCG/100 MCG AEROSOL İNHALASYONU, SÜSPANSİYON (200 DOZ), İPRALEV 20 MCG/50 MCG AEROSOL İNHALASYONU,SÜSPANSİYON, 200 DOZProducts: ATROVENT 500 MG /2ML, ATROVENT 500 MCG/2 ML TEK DOZLUK INHALASYON SOLUSYON 20 FLAKONColistin
go.drugbank.com/drugs/DB00803ApprovedInvestigationalIt is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes.
Products: APSASOL COLISTIN Powder 100 mg/g, Rican Premix Powder 1,900 IU/mgEtravirine
go.drugbank.com/drugs/DB06414ApprovedInvestigationalOn March 26, 2012, approval was extended for use in treatment-experienced pediatric patients 6 to 18 years of age, weighing at least 16 kg. … In 2013, reports of Autoimmune disorders (such as Graves’ disease, polymyositis, and Guillain-Barré syndrome) in the setting of immune reconstitution, as well as more in depth information about the development
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: INTELENCE 100 MG TABLETS, INTELENCE 100 MG TABLET, 120 ADET