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Seviteronel
go.drugbank.com/drugs/DB12275InvestigationalSeviteronel has been used in trials studying the treatment of CRPC, Prostate Cancer, and Castration-resistant Prostate Cancer.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 Enzyme InhibitorsLuspatercept
go.drugbank.com/drugs/DB12281ApprovedInvestigationalLuspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human IgG1. … [A187829,L42455] It was first approved for use in the United States in November 2019 under the brand name Reblozyl® for the treatment of anemia in patients with beta thalassemia who require regular blood
Products: REBLOZYL®LY-2608204
go.drugbank.com/drugs/DB12284InvestigationalLY2608204 has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
Categories: Heterocyclic Compounds, 1-RingVerubecestat
go.drugbank.com/drugs/DB12285InvestigationalVerubecestat is Merck’s investigational oral β-site amyloid precursor protein cleaving enzyme (BACE1 or β secretase) inhibitor. … In the study, administration of Verubecestat at doses of 12, 40 and 60 mg resulted in a dose-dependent and sustained reduction in the levels of Ab40, a measure of BACE1 activity, in CSF from baseline of
Categories: Heterocyclic Compounds, 1-RingSimendan
go.drugbank.com/drugs/DB12286ExperimentalCategories: Heterocyclic Compounds, 1-Ring, Phosphodiesterase 3 InhibitorsPiromelatine
go.drugbank.com/drugs/DB12288InvestigationalPiromelatine has been used in trials studying the treatment of Alzheimer's Disease.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingPuerarin
go.drugbank.com/drugs/DB12290InvestigationalPuerarin has been investigated for the treatment of Alcohol Abuse.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingNefopam
go.drugbank.com/drugs/DB12293ApprovedInvestigationalWithdrawnNefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. Nefopam has been investigated for the prevention of Kidney Transplantation.
Categories: Heterocyclic Compounds, 1-RingProducts: KATAMOX® SOLUCIÓN INYECTABLEEvodenoson
go.drugbank.com/drugs/DB12295InvestigationalEvodenoson has been used in trials studying the treatment of Open-angle Glaucoma and Ocular Hypertension.
Categories: Heterocyclic Compounds, 1-RingGLPG-0187
go.drugbank.com/drugs/DB12297InvestigationalGLPG0187 has been used in trials studying the treatment of Solid Tumors.
Categories: Heterocyclic Compounds, 2-Ring