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Displaying results 5691 - 5700 of 10000 in total
  1. Drug

    OAV201

    go.drugbank.com/drugs/DB17842
    Experimental

    It was first developed by Novartis and investigated for the treatment of Rett syndrome, but further investigation in clinical trials was halted.[L46661] … OAV201 is a non-replicating, recombinant adeno-associated virus serotype 9 (AAV9) containing the human Methyl CpG Binding Protein 2B (MECP2B) cDNA under the control of a segment of the murine MECP2 promoter

  2. Drug

    AICA ribonucleotide

    go.drugbank.com/drugs/DB01700
    Investigational

    5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate and analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent … The drug was first used in the 1980s as a method to preserve blood flow to the heart during surgery and is currently of interest as a potential treatment for diabetes by increasing the metabolic activity

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  3. Drug

    Rhodotorula rubra

    go.drugbank.com/drugs/DB10442
    Approved

    Rhodotorula rubra is a fungus which can provoke allergic reactions. Rhodotorula rubra is used in allergenic testing.

  4. Drug

    Rhodotorula mucilaginosa

    go.drugbank.com/drugs/DB10701
    Approved

    Rhodotorula mucilaginosa is a fungus which can provoke allergic reactions. Rhodotorula mucilaginosa is used in allergenic testing.

  5. Drug

    Candida tropicalis

    go.drugbank.com/drugs/DB10807
    Approved

    Candida tropicalis is a fungus which can provoke allergic reactions. Candida tropicalis is used in allergenic testing.

  6. Drug

    Besifloxacin

    go.drugbank.com/drugs/DB06771
    Approved

    Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. FDA approved on May 28, 2009.

    Categories: Topoisomerase II Inhibitors
  7. Drug

    Pantethine

    go.drugbank.com/drugs/DB11190
    Approved

    It consists of two molecules of pantetheine that form a dimer via disufide linkages, and acts as an intermediate in the production of Coenzyme A. … Coenzyme A plays an essential role as a cofactor in the metabolism of lipids and carbohydrates including fatty acid oxidation, carbohydrate metabolism, pyruvate degradation, and amino acid catabolism [

    Synonyms: D-Bis(N-pantothenyl-beta-aminoethyl) disulfideCategories: Alimentary Tract and Metabolism
  8. Drug

    CR002

    go.drugbank.com/drugs/DB05139
    Investigational

    CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived growth factor-D (PDGF-D), a target shown to play a role in kidney inflammation. … This is a novel therapeutic approach to treat kidney inflammation.

    Categories: Amino Acids, Peptides, and Proteins
  9. Indication

    Gastrointestinal Cancers - Anus

    go.drugbank.com/conditions/DBCOND0145654
    Drugs: Mitomycin
    Synonyms: Ca anus, (Ca anus) or (anus carcinoma)
  10. Drug

    AG-858

    go.drugbank.com/drugs/DB05502
    Investigational

    Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity and tumor-specific T cells in animal models. … AG-858 (autologous heat-shock protein 70 peptide vaccine) is a recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes.