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QS-21
go.drugbank.com/drugs/DB05400InvestigationalQS-21 is an investigational adjuvant, which is a substance added to vaccines and other immunotherapies that is designed to enhance the body’s immune response to the antigen contained within the treatment … As a vaccine additive, it is currently being evaluated in clinical trials in a variety of disease areas by Antigenics.
N-Methylmesoporphyrin
go.drugbank.com/drugs/DB01911ExperimentalThese are compounds containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to form a macrocyclic structure.
HMR4011
go.drugbank.com/drugs/DB06225ExperimentalHMR4011 (IPL 576,092) is a novel steroidal anti-inflammatory compound with a mechanism of action distinct from that of glucocorticoid.
Octamoxin
go.drugbank.com/drugs/DB09249ApprovedWithdrawnOctamoxin, also known as _2-octylhydrazine_, is both an irreversible and nonselective monoamine oxidase enzyme inhibitor (MAOI) of the _hydrazine_ chemical class. … This drug was used in the past as an antidepressant agent in the 1960s, however, has since been discontinued.
Vibrio cholerae Inaba 6973 El Tor biotype, formalin inactivated
go.drugbank.com/drugs/DB15484ApprovedInvestigationalMixtures: DUKORAL VACCINE AGAINST CHOLERA AND ETEC-DIARRHOEAZytron
go.drugbank.com/drugs/DB11768ApprovedWithdrawnZytron (DMPA) is under investigation for the treatment and health services research of HIV, Lactation, Contraception, Postpartum Depression, and Immune Cells (Mucosal and Systemic). … DMPA has been investigated for the prevention, treatment, and basic science of Weight and Microbiota.
UCB7362
go.drugbank.com/drugs/DB17096Experimental[A254222] Plasmepsins are aspartyl proteases produced by the malaria parasite _Plasmodium falciparum_, and PMX is considered to be essential for parasite egress and invasion. … UCB7362 is an orally active plasmepsin X (PMX) inhibitor currently investigated for the treatment of malaria.
Dilmapimod
go.drugbank.com/drugs/DB12140InvestigationalDilmapimod has been used in trials studying the treatment and diagnostic of Nerve Trauma, Inflammation, Pain, Neuropathic, Arthritis, Rheumatoid, and Coronary Heart Disease, among others. … Previous p38 MAP-kinase inhibitors have been hindered in development by liver toxicity. Methotrexate (common treatment for RA patients) also has potential liver toxicity.}
Egaptivon pegol
go.drugbank.com/drugs/DB05202Investigationalaggregation under the high shear conditions of coronary arterial stenosis and plaque rupture. … Egaptivon pegol is being investigated for the treatment of thrombotic thrombocytopenic purpura and acute coronary syndromes.
Categories: Nucleic Acids, Nucleotides, and NucleosidesGallium chloride Ga-67
go.drugbank.com/drugs/DB14550ApprovedGallium chloride Ga-67 is the chloride salt of a gallium radioisotope which is typically complexed with [sodium citrate] to generate [gallium citrate Ga 67], which can be used to image certain cancers and