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RP-L301
go.drugbank.com/drugs/DB17661InvestigationalRP-L301 is a lentiviral vector containing the human liver and erythroid pyruvate kinase gene.
Epirizole
go.drugbank.com/drugs/DB08991ExperimentalEpirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain.
Categories: Analgesics, Non-Narcotic, Non COX-2 selective NSAIDSSitimagene ceradenovec
go.drugbank.com/drugs/DB04907ExperimentalSitimagene ceradenovec is a novel gene-based product for the treatment of patients with operable high grade glioma, a type of malignant brain tumour, given in addition to standard surgery and radiotherapy … It is being developed by Ark Therapeutics.
Thenyldiamine
go.drugbank.com/drugs/DB16022ApprovedWithdrawnMixtures: Neo Synephrine Nasal Spray, Neo-synephrine Nasal SprayRolofylline
go.drugbank.com/drugs/DB12670InvestigationalRolofylline is under clinical development by pharmaceutical company NovaCardia for the treatment of congestive heart failure.
J147
go.drugbank.com/drugs/DB13957Experimental[A31606,A31607,A31608] It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate initially developed for the treatment of neurodegenerative conditions associated with aging … J147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesSynonyms: N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N'-[(E)-(3-methoxyphenyl)methylene]acetohydrazideXC221
go.drugbank.com/drugs/DB16503InvestigationalXC221 was investigated in clinical trials to treat patients with respiratory infections, including influenza, COVID-19, and other acute viral upper respiratory infections.
Categories: Experimental Unapproved Treatments for COVID-19Pelacarsen
go.drugbank.com/drugs/DB16284InvestigationalPelacarsen is under investigation in clinical trial NCT03070782 (Phase 2 Study of ISIS 681257 (Akcea-apo(a)-lrx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease).
Synonyms: AKCEA-APO(a)-LRx, IONIS-APO(a)-LRxPeoniflorin
go.drugbank.com/drugs/DB16288InvestigationalPeoniflorin is under investigation in clinical trial NCT02878863 (Paeoniflorin Combination of Hepatoprotective Drugs Versus Hepatoprotective Drugs Only for Auto-immune Hepatitis).
Categories: Analgesics, Non-Narcotic, Anti-Inflammatory Agents, Non-SteroidalMRK-003
go.drugbank.com/drugs/DB17015ExperimentalMRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of [MK-0752], a drug in clinical development.[A252682]
Synonyms: (1'R,4R)-2-(2,2,2-trifluoroethyl)-5'-[(E)-3-[4-(trifluoromethyl)piperidin-1-yl]prop-1-enyl]spiro[1,2,5-thiadiazolidine-4,13'-tricyclo[8.2.1.03,8]trideca-3(8),4,6-triene] 1,1-dioxide