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Displaying results 5701 - 5710 of 10000 in total
  1. Drug

    Mevastatin

    go.drugbank.com/drugs/DB06693
    Experimental

    Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 times greater than the HMG-CoA substrate itself. … During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that appeared to lower plasma cholesterol levels.

  2. Drug

    Abivertinib

    go.drugbank.com/drugs/DB15327
    Investigational

    Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth factor receptor (EGFR) and Bruton's tyrosine kinase (BTK). … cytokines at once, it may provide more pronounced clinical benefits as compared to agents targeting single pathways (e.g. interleukin-6 inhibitors).

  3. Drug

    Becocalcidiol

    go.drugbank.com/drugs/DB04891
    Investigational

    Becocalcidiol is a vitamin D(3) analogue which has not caused hypercalcaemia or significant irritation in preclinical trials.

  4. Drug

    1-benzylimidazole

    go.drugbank.com/drugs/DB04581
    Experimental

    1-benzylimidazole, an N-imidazole derivative, has been shown to have strong cardiotonic activity.

  5. Drug

    Isunakinra

    go.drugbank.com/drugs/DB12373
    Investigational

    Isunakinra has been investigated for the treatment of Dry Eye and Allergic Conjunctivitis (AC).

    Categories: Interleukin-1 Receptor Antagonist
  6. Drug

    ARCT-810

    go.drugbank.com/drugs/DB17683
    Investigational

    ARCT-810 is an mRNA replacement therapy that delivers ornithine transcarbamylase mRNA to hepatocytes.

  7. Drug

    AMT-162

    go.drugbank.com/drugs/DB17922
    Investigational

    AMT-162 is an adeno-associated virus serotype rh10 encoding artificial anti-SOD1 miRNA.

  8. Drug

    Tildacerfont

    go.drugbank.com/drugs/DB18545
    Investigational

    Tildacerfont is a corticotropin-releasing factor receptor-1 antagonist containing an unfused thiazole ring

    Synonyms: Pyrazolo(1,5-a)pyrimidine, 3-(4-chloro-2-(4-morpholinyl)-5-thiazolyl)-7-(1-ethylpropyl)-2,5-dimethyl-pyrazolo(1,3-a)pyrimidine, 3-(5-chloro-2-morpholin-4-yl-thiazol-4-yl)-7-(1-ethyl-propyl)-2,5-dimethyl-pyrazolo(1,5-a)pyrimidine
  9. Drug

    Diethyltryptamine

    go.drugbank.com/drugs/DB01460
    ExperimentalIllicit

    Diethyltryptamine (DET) is an orally active hallucinogenic agent and a substituted form of tryptamine.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Triphosphoric acid

    go.drugbank.com/drugs/DB03896
    Experimental

    Used as water softener, peptizing agent, emulsifier & dispersing agent; ingredient of cleansers; meat preservative.