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Cyclopropane
go.drugbank.com/drugs/DB13984ExperimentalInstead, it turned out to be an excellent anesthetic with very rapid onset and recovery while maintaining stable hemodynamics. Its use was ultimately limited because it was highly explosive.
Prolectin-M
go.drugbank.com/drugs/DB16521InvestigationalProlectin-M is a (1-6)-alpha-D-mannopyranose[L31338] and acts as an antagonist of galectin.
Cetrelimab
go.drugbank.com/drugs/DB15421InvestigationalCetrelimab is under investigation in clinical trial NCT03547037 (A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of JNJ-63723283, an Anti-Programmed Cell Death (PD
AVI-7537
go.drugbank.com/drugs/DB15433InvestigationalAVI-7537 is an antisense molecule that binds to the Ebola virus mRNA to prevent the viral replication.
RP01
go.drugbank.com/drugs/DB05751ExperimentalIt is designed to induce the immune system to produce antibodies that block Immunoglobulin E (IgE), the key mediator of an allergic response.
Belnacasan
go.drugbank.com/drugs/DB05507InvestigationalVX-765 is currently under clinical development for the treatment of inflammatory and autoimmune conditions, as it blocks the hypersensitive response to an inflammatory stimulus.
Methoxy arachidonyl fluorophosphonate
go.drugbank.com/drugs/DB02465ExperimentalMethoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases.
TM5614
go.drugbank.com/drugs/DB16516InvestigationalAn animal study in mice fed a fast-food diet with TM5614 treatment showed improved metabolic measurements and reduced liver steatosis[L31673,L31678]. … Further investigation of this compound is underway, including an exploratry Phase II study for its efficacy and safety for high-risk hospitalized patients with severe COVID-19 pneumonia[L31688].
Taspoglutide
go.drugbank.com/drugs/DB14027InvestigationalTaspoglutide is a pharmaceutical drug, a glucagon-like peptide-1 agonist (GLP-1 agonist), under investigation for treatment of type 2 diabetes being codeveloped by Ipsen and Roche.