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Displaying results 5741 - 5750 of 10000 in total
  1. Drug

    Chlormezanone

    go.drugbank.com/drugs/DB01178
    ApprovedWithdrawn

    A non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.

    Categories: Oxazol, Thiazine, and Triazine DerivativesSynonyms: 2-(p-chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxide
  2. Drug

    Esmirtazapine

    go.drugbank.com/drugs/DB06678
    Investigational

    Esmirtazapine, known by the standardized identifier SCH 900265, was under development by Organon to treat insomnia and vasomotor symptoms associated with menopause. … Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology.

  3. Drug

    PSN357

    go.drugbank.com/drugs/DB05044
    Experimental

    PSN357 is a glycogen phosphorylase inhibitor (GPI), which is designed to rapidly lower blood glucose levels by preventing glycogen breakdown to glucose in the liver.

  4. Drug

    NM-702

    go.drugbank.com/drugs/DB05505
    Investigational

    M-702 is an orally active inhibitor of phosphodiesterase and thromboxane synthetase. … In Japan, Phase 2 studies are being conducted for intermittent claudication caused by arteriosclerosis obliterans, intermittent claudication caused by spinal canal stenosis, and asthma.

  5. Drug

    Tubercidin

    go.drugbank.com/drugs/DB03172
    Experimental

    An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  6. Drug

    CoviGlobulin

    go.drugbank.com/drugs/DB15747
    Experimental

    The antibodies themselves are produced in response to an immunogen and derived from antibody-producing plasma cells that were once B-cell clones. … Current applications of antibodies include, but are not limited to, targeting cancer, inflammatory diseases, organ transplantation, cardiovascular disease, infection, respiratory disease, and ophthalmologic

  7. Drug

    Xylazine

    go.drugbank.com/drugs/DB11477
    InvestigationalVet approved

    Xylazine is a clonidine analog used as a non-opioid tranquilizer in veterinary medicine and as an emetic, especially in cats. … [A9096] The use of xylazine can lead to hypotension and bradycardia[A9092,A9093], and when combined with central nervous system depressants, such as benzodiazepines or alcohol, it can significantly depress

    Categories: Hypnotics and Sedatives
  8. Drug

    Triazavirin

    go.drugbank.com/drugs/DB15622
    Investigational

    [A191709,A191625,A191916] It appears that Triazavirin has shown promise in reducing influenza disease severity and associated complications. … [L12087] Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating Triazavirin as an option to combat SARS-CoV-2, the coronavirus responsible for COVID-19.[A191625]

  9. Drug

    Utidelone

    go.drugbank.com/drugs/DB17575
    Investigational

    Utidelone (UTD1), a novel microtubule stabilizing agent, is an epothilone B analogue produced by genetic engineering.[A257544,A257549] It is under investigation in clinical trials for various cancers.

    Categories: Antineoplastic and Immunomodulating Agents, Cytotoxic Antibiotics and Related Substances
  10. Indication

    Advanced Gastric Carcinoma

    go.drugbank.com/conditions/DBCOND0032323
    Drugs: Hyaluronidase (human recombinant) · Nivolumab
    Synonyms: Ca stomach NOS, CA - Cancer of stomach