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Displaying results 5741 - 5750 of 5758 in total

Drug
Glycochenodeoxycholic Acid
go.drugbank.com/drugs/DB02123
Experimental
A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic. [PubChem]
Categories: N-substituted Glycines
Drug
Equilin
go.drugbank.com/drugs/DB02187
Experimental
An estrogenic steroid produced by horses. It has a total of four double bonds in the A- and B-ring. High concentration of equilin is found in the urine of pregnant mares.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
Drug
Ditiocarb
go.drugbank.com/drugs/DB02520
Investigational
A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.
Categories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP3A Inhibitors
Drug
Peldesine
go.drugbank.com/drugs/DB02568
Investigational
Peldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections.
Categories: N-Glycosyl Hydrolases, antagonists & inhibitors, Cytochrome P-450 Substrates
Drug
Pregnenolone
go.drugbank.com/drugs/DB02789
ApprovedInvestigationalWithdrawn
A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
Drug
Patupilone
go.drugbank.com/drugs/DB03010
Investigational
Epothilone B is a 16-membered macrolide that mimics the biological effects of taxol.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
Drug
Phencyclidine
go.drugbank.com/drugs/DB03575
ExperimentalIllicit
It exerts its pharmacological action through inhibition of NMDA receptors (receptors, N-methyl-D-aspartate). As a drug of abuse, it is known as PCP and Angel Dust.
Categories: Cytochrome P-450 CYP2B6 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
Drug
Vanoxerine
go.drugbank.com/drugs/DB03701
Investigational
Vanoxerine is a highly selective dopamine transporter antagonist. It was synthesized in the late 1970s and developed as a potential treatment for depression. Vanoxerine was later evaluated as a potential treatment for cocaine addiction d...
Synonyms: 1-(2-(bis(p-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
Drug
N-acetyl-alpha-D-glucosamine
go.drugbank.com/drugs/DB03740
Experimental
The N-acetyl derivative of glucosamine.
Synonyms: N-acetyl-α-D-glucosamine, N-acetyl-alpha-D-glucosamine
Drug
N-acetyl-beta-neuraminic acid
go.drugbank.com/drugs/DB04265
Experimental
An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
Synonyms: N-acetyl-β-neuraminic acid, N-acetyl-beta-neuraminic acid