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Displaying results 5741 - 5750 of 10000 in total
  1. Drug

    Anpocogin

    go.drugbank.com/drugs/DB06552
    Investigational

    Recombinant nematode anticoagulant protein c2 (rNAPc2) is a specific inhibitor of tissue factor (TF)/factor VIIa complex with novel antithrombotic activity. [A175642]

  2. Drug

    Axitinib

    go.drugbank.com/drugs/DB06626
    ApprovedInvestigational

    [L6676] Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. … It is reported to exhibit potency that is 50-450 times higher than that of the first generation VEGFR inhibitors.[L6676] Axitinib is an indazole derivative.

    Products: INLYTA (TABLETS 1 MG), INLYTA (TABLETS 5 MG)
  3. Drug

    Bafilomycin A1

    go.drugbank.com/drugs/DB06733
    Experimental

    The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus. … This is a useful tool as it can prevent the re-acidification of synaptic vesicles once they have undergone exocytosis.

  4. Drug

    MVA3000

    go.drugbank.com/drugs/DB05040
    Experimental

    MVA3000 is an attenuated smallpox vaccine that is being developed for use in people for whom the traditional smallpox vaccine is contraindicated, such as patients with disorders of the immune system or

  5. Drug

    Arlocabtagene autoleucel

    go.drugbank.com/drugs/DB24024
    Investigational

    Arlocabtagene Autoleucel is under investigation in clinical trial NCT06297226 (Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or

  6. Drug

    Black widow spider antivenin (equine)

    go.drugbank.com/drugs/DB14113
    Approved

    Black widow spider (_Latrodectus mactans_) antivenin is a treatment for black widow spider bites derived from the serum of healthy horses immunized against black widow spider venom.[L12792]

  7. Drug

    Rebaudioside A

    go.drugbank.com/drugs/DB15136
    Investigational

    Rebaudioside A is under investigation in clinical trial NCT03510624 (Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus).

  8. Drug

    Silmitasertib

    go.drugbank.com/drugs/DB15408
    Investigational

    Silmitasertib is under investigation in clinical trial NCT03904862 (Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery).

  9. Drug

    VGV-1

    go.drugbank.com/drugs/DB05328
    Experimental

    VGV-1 is a potential salvage therapy for treatment of HIV infected people who have failed anti-retroviral therapy.

  10. Drug

    INCB7839

    go.drugbank.com/drugs/DB05033
    Investigational

    INCB7839 is a novel, orally available ADAM metalloprotease inhibitor that is designed to block activation of the epidermal growth factor (EGFR) pathways. … It represents a potentially important new class of targeted breast cancer therapy. It has shown promising clinical activity in heavily pretreated, refractory breast cancer patients.