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Displaying results 5751 - 5760 of 10000 in total
  1. Drug

    Telithromycin

    go.drugbank.com/drugs/DB00976
    Approved

    It is used to treat mild to moderate respiratory infections. … Binding occurs simultaneously at to two domains of 23S RNA of the 50S ribosomal subunit, domain II and V, where older macrolides bind only to one.

  2. Drug

    Gaboxadol

    go.drugbank.com/drugs/DB06554
    Investigational

    Gaboxadol also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) is an experimental sleep aid drug developed by Lundbeck and Merck, who reported increased deep sleep without the reinforcing … Development of Gaboxadol was stopped in March 2007 after concerns regarding safety and efficacy. It acts on the GABA system, but in a seemingly different way from benzodiazepines and other sedatives.

  3. Drug

    Clopenthixol

    go.drugbank.com/drugs/DB13841
    Investigational

    Clopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.

  4. Drug

    Apc001

    go.drugbank.com/drugs/DB17819
    Experimental

    Apc001 is an aptamer developed for the treatment of osteogenesis imperfecta.

  5. Drug

    HLX-58

    go.drugbank.com/drugs/DB18699
    Experimental

    HLX-58 is an investigational monoclonal antibody targeted against claudin 18.2.

  6. Drug

    BA1301

    go.drugbank.com/drugs/DB19390
    Investigational

    BA1301 is an anti-Claudin18.2 monoclonal antibody conjugated with Duostatin-5.

  7. Drug

    Clorobiocin

    go.drugbank.com/drugs/DB03966
    Experimental

    Clorobiocin is an aminocoumarin antibiotic, similar to [novobiocin] and coumermycin A1.

  8. Drug

    Brazikumab

    go.drugbank.com/drugs/DB16115
    Investigational

    Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease).

  9. Drug

    Foralumab

    go.drugbank.com/drugs/DB16170
    Investigational

    Foralumab is under investigation in clinical trial NCT03291249 (Assessment of the Safety of Foralumab, an Oral Anti-cd3 Antibody, in Patients With NASH and T2DM).

  10. Drug

    ATX-F8-117

    go.drugbank.com/drugs/DB17712
    Experimental

    ATX-F8-117 is an investigational peptide derived from Factor VIII. Developed by Apitope, it is being investigated for the treatment of hemophilia A.[L46163]