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Displaying results 5761 - 5770 of 8974 in total
  1. Drug

    Loprazolam

    go.drugbank.com/drugs/DB13643
    Experimental

    It is indicated for the short-term treatment of insomnia including difficulty in falling asleep and/or frequent nocturnal awakenings. … Loprazolam is recommended as a short-term therapy only, due to adverse events associated with the drug including dependence and withdrawal symptoms.

  2. Drug

    Drotrecogin alfa

    go.drugbank.com/drugs/DB00055
    ApprovedWithdrawn

    Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. … It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond.

  3. Drug

    Pegsitacianine

    go.drugbank.com/drugs/DB19098
    Investigational

    Imaging Agent for the Detection of Cancer, in Patients With Unknown Primary Head and Neck Cancer (ILLUMINATE STUDY)). … Pegsitacianine is under investigation in clinical trial NCT05576974 (A Phase 2a, Single-dose, Open-label Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence

  4. Drug

    3-Methylfentanyl

    go.drugbank.com/drugs/DB01571
    ExperimentalIllicit

    3-Methylfentanyl is an opioid analgesic and is an analog of the potent opioid, fentanyl. 3-Methylfentanyl is one of the most powerful opioid drugs sold illegally and is estimated to be between 400-6000

  5. Drug

    Desmoteplase

    go.drugbank.com/drugs/DB04925
    Investigational

    It activates plasminogen to the serine protease, plasmin. Plasmin acts by breaking down fibrin blood clots. … Desmoteplase is a recombinant form of vampire bat DSPA (Salivary plasminogen activator alpha 1).

  6. Drug

    Amperozide

    go.drugbank.com/drugs/DB08927
    Experimental

    Investigations regarding the use of the agent revolved primarily around its capability for treating schizophrenia in humans even though the drug was ultimately never clinically adopted for this indication … Alternatively, amperozide's main use lies in veterinary medicine, where it is typically employed to minimize aggression and stress in intensively farmed pigs.

  7. Drug

    Afabicin

    go.drugbank.com/drugs/DB15268
    Investigational

    Afabicin is under investigation in clinical trial NCT03723551 (Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus

  8. Drug

    Pipendoxifene

    go.drugbank.com/drugs/DB05414
    Investigational

    for metastatic breast cancer. … ER modulator, ERA-923(Pipendoxifene) is a estrogen receptor modulator being evaluated for the treatment of breast cancer.

  9. Drug

    Cetuximab sarotalocan

    go.drugbank.com/drugs/DB19240
    Investigational

    Cetuximab sarotalocan is under investigation in clinical trial NCT03769506 (ASP-1929 Photoimmunotherapy (PIT) Study in Recurrent Head/Neck Cancer for Patients Who Have Failed at Least Two Lines of Therapy … ) for the treatment of Recurrent Head/Neck Cancer.

  10. Drug

    AVR-RD-01

    go.drugbank.com/drugs/DB17651
    Investigational

    AVR-RD-01 is being investigated for Fabry Disease.[L45963, L45968] … AVR-RD-01 is an investigational _ex vivo_ lentiviral gene therapy developed by AVROBIO Inc.