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Acellular nerve allograft
go.drugbank.com/drugs/DB30293ApprovedInvestigationalOur team is working on the full update, which will be available soon. [L54673,L54668] … Approved by the FDA under a Biologics License Application (BLA) as an acellular nerve scaffold for the treatment of adult and pediatric patients (aged ≥1 month) with sensory, mixed, and motor peripheral
Metrifonate
go.drugbank.com/drugs/DB11473ExperimentalVet approvedMetrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
Categories: Compounds used in a research, industrial, or household settingSynonyms: 1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl esterRanpirnase
go.drugbank.com/drugs/DB04950InvestigationalRanpirnase is a ribonuclease enzyme found in <i>Rana pipiens</i> oocytes. It is being studied in the treatment of cancer. It is manufactured by Alfacell Corporation. … It is the first ribonuclease to enter cancer clinical trials.
Poliovirus type 2 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10796ApprovedInvestigationalPoliovirus type 2 antigen is a suspension of poliovirus Type 2 (MEF-1) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis … caused by poliovirus Type 2.
Mixtures: HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET, TETRAXIM 0.5 ML IM ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETSynonyms: Inactivated poliovirus type II, Poliovirus vaccine inactivated, type 2 (MEF-1)Tavaborole
go.drugbank.com/drugs/DB09041ApprovedTavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to *Trichophyton rubrum* or *Trichophyton mentagrophytes … Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis of ATP-dependent ligation of L-leucine to tRNA(Leu).
Synonyms: 5-Fluoro-2,1-benzoxaborol-1(3H)-ol, 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaboroleMelarsomine
go.drugbank.com/drugs/DB11528ExperimentalVet approvedMelarsomine is a trypanocidal agent marketed by Merial under the trade name Immiticide. … It is the only FDA-approved treatment for adult heartworm infection in dogs, however, is is not approved for use in dogs with late-stage infection.
Categories: Heterocyclic Compounds, 1-RingChlorhexadol
go.drugbank.com/drugs/DB01534IllicitInvestigationalChlorhexadol is a sedative and hypnotic which is regulated in the United States as a Schedule III controlled substance. It is a derivative of chloral hydrate.
Chlorambucil
go.drugbank.com/drugs/DB00291ApprovedInvestigationalAlthough it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed) … A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases.
Synonyms: N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid, γ-[p-di(2-chloroethyl)aminophenyl]butyric acidProducts: ลูเคอแรน (เม็ด 2 มก.), Leukeran 2 mg - FilmtablettenDexfenfluramine
go.drugbank.com/drugs/DB01191ApprovedIllicitWithdrawnDexfenfluramine, also marketed under the name Redux, is a serotoninergic anorectic drug. … For a fairly limited time during the middle of the nineties, the US FDA had approved it for use in managing weight loss.
Synonyms: (S)-fenfluramine, (S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates