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Displaying results 571 - 580 of 10000 in total
  1. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    Approved

    Additionally, it does not appear to lessen symptoms associated with constipation such as abdominal cramps. Still docusate is available in over-the-counter products as a common laxative. … Docusate is on the World Health Organization's List of Essential Medicines[L5915].

    Mixtures: Tl-hem 150, TL-SelectProducts: healthy mama MOVE IT ALONG, Soflax Dps 10mg/ml
  2. Drug

    Acetylcysteine

    go.drugbank.com/drugs/DB06151
    ApprovedInvestigational

    Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose.

    Mixtures: AKE 1100 GLUKOZLU IV SOLOSYONU, 500 ML, AKE 1100 GLUKOZLU IV SOLOSYONU, 1000 MLCategories: Compounds used in a research, industrial, or household setting
  3. Target

    Interleukin-2

    go.drugbank.com/bio_entities/BE0001029
    TargetHumans

    Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG) (PubMed:16293754, PubMed:16477002 … Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3 (PubMed:7973659).

    Synonyms: IL-2
  4. Drug

    Levosimendan

    go.drugbank.com/drugs/DB00922
    ApprovedInvestigationalWithdrawn

    Levosimendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure). … It also relaxes vascular smooth muscle by opening adenosine triphosphate sensitive potassium channels. Levosimendan is used to manage acutely decompensated congestive heart failure.

    Categories: Compounds used in a research, industrial, or household settingProducts: SİMELEV 12,5 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, SIMDAX 2.5 MG/ML KONSANTRE INF.COZ.5 ML X FLAKON, 1 ADET
  5. Drug

    Latanoprost

    go.drugbank.com/drugs/DB00654
    ApprovedInvestigational

    Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. … Another benefit latanoprost is that it can be administered once a day.[A184490]

    Mixtures: Fixapost 50 Mikrogramm/ml + 5 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis, LATANOMED CO50UG/ML+5MG/MLCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Naloxone

    go.drugbank.com/drugs/DB01183
    ApprovedInvestigationalVet approved

    Also known as the brand name product Narcan, naloxone is currently available by intramuscular (IM) or subcutaneous (SubQ) injection, nasal spray, or intravenous (IV) infusion. … [L33724] Naloxone is indicated for the rapid reversal of these symptoms of central nervous system depression in opioid overdose.

    Mixtures: TILIDIN AL COMP, TILIDIN AL COMPProducts: Naloxon Accord 0,4 mg/ml Injektions-/Infusionslösung in einer Fertigspritze, NALOXONA 0.4 MG/ML
  7. Target

    Interleukin-22 receptor subunit alpha-1

    go.drugbank.com/bio_entities/BE0016650
    TargetHumans

    Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of ...

    Synonyms: IL-22RA1, IL-22R-alpha-1
  8. Drug

    Nicotine

    go.drugbank.com/drugs/DB00184
    ApprovedInvestigational

    Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. … Nicotine is also important medically because of its presence in tobacco smoke.

    Categories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine DependenceSynonyms: L(−)-nicotine, (S)-3-(1-methylpyrrolidin-2-yl)pyridine
  9. Drug

    Formoterol

    go.drugbank.com/drugs/DB00983
    ApprovedInvestigational

    Formoterol is an inhaled beta<sub>2</sub>-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. … [L11256] It is available as a single-entity product [L10986,L11223] and in several formulations in combination with both inhaled corticosteroids [L10995,L10619] and long-acting muscarinic antagonists.

    Products: CYCLOCAPS FORMOTERO12UG+IN, FORMATRIS 12UG NOV I+2PX60
  10. Target

    Interleukin-36 alpha

    go.drugbank.com/bio_entities/BE0020856
    TargetHumans

    -8 and IL-6. … In cultured monocytes up-regulates expression of IL-1A, IL-1B and IL-6. In myeloid dendritic cells involved in cell maturation by up-regulating surface expression of CD83, CD86 and HLA-DR.

    Synonyms: IL-1F6, IL-1 epsilon