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Displaying results 571 - 580 of 10000 in total
  1. Drug

    Itraconazole

    go.drugbank.com/drugs/DB01167
    ApprovedInvestigational

    [L50051] Itraconazole was first approved in the US in 1992 [L50056] and is available orally. … While the intravenous formulation of the drug was formerly available, it was discontinued in the US in 2007.[A263232]

    Products: ITRACONAZOLO EG
  2. Drug

    Metronidazole

    go.drugbank.com/drugs/DB00916
    ApprovedInvestigational

    It is available in capsule form, tablet form, and topical form, and suppository preparations for the treatment of various infections. … [A181036,A181039] Metronidazole has been used as an antibiotic for several decades[L7429], with added antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat

    Mixtures: METARSAL N CAPSULAS, FUROTIL-N (METRONIDAZOL 600MG NIFUROXAZIDE 200MG)Products: Flagyl ER, Florazole ER
  3. Drug

    Leuprolide

    go.drugbank.com/drugs/DB00007
    ApprovedInvestigational

    Prolonged activation of GnRHR results in significant downregulation of sex steroid levels, which is primarily responsible for the clinical efficacy of leuprolide in diverse conditions, including advanced … [L13781, L13790] Leuprolide remains frontline therapy in all conditions for which it is indicated for use.

    Products: ELIGARD 22.5 MG ENJ. COZ. ICIN S.C. TOZ ICEREN SIRINGA VE COZUCU ICEREN SIRINGA, 1 ADET
  4. Drug

    Darunavir

    go.drugbank.com/drugs/DB01264
    ApprovedInvestigational

    [A2278,A2281] It was initially approved by the FDA in 2006. … [A191682] Clinical trials are underway and are expected to conclude in August 2020.[L12066]

    Mixtures: VIRONTAR N COMPRIMIDOS RECUBIERTOS, VIRONTAR N COMPRIMIDOS RECUBIERTOSCategories: Antivirals used in combination for the treatment of HIV infections
  5. Drug

    Sunitinib

    go.drugbank.com/drugs/DB01268
    ApprovedInvestigational

    In addition, sunitinib inhibits other RTKs including RET, CSF-1R, and flt3. … For these purposes, sunitinib is generally available as an orally administered formulation. Sunitinib inhibits cellular signaling by targeting multiple RTKs.

    Products: SUNITINIB EG
  6. Target

    Cytochrome b-c1 complex subunit 8

    go.drugbank.com/bio_entities/BE0003857
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.

    Polypeptides: Cytochrome b-c1 complex subunit 8Synonyms: Complex III subunit 8, Complex III subunit VIII
  7. Target

    Cytochrome b-c1 complex subunit 9

    go.drugbank.com/bio_entities/BE0003861
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.

    Polypeptides: Cytochrome b-c1 complex subunit 9Synonyms: Complex III subunit 9, Complex III subunit X
  8. Target

    Cytochrome b6-f complex subunit 5

    go.drugbank.com/bio_entities/BE0003906
    TargetMastigocladus laminosus

    PetG is required for either the stability or assembly of the cytochrome b6-f complex. … Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.

    Polypeptides: Cytochrome b6-f complex subunit 5Synonyms: Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V
  9. Target

    Fatty acid oxidation complex subunit alpha

    go.drugbank.com/bio_entities/BE0004256
    TargetPseudomonas fragi

    Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-Co...

    Polypeptides: Fatty acid oxidation complex subunit alpha
  10. Target

    Trafficking protein particle complex subunit 4

    go.drugbank.com/bio_entities/BE0004278
    TargetHumans

    Core component of the TRAPP complexes which has a function of guanine nucleotide exchange factor activity for Rab1 GTPase (Probable).

    Polypeptides: Trafficking protein particle complex subunit 4