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Displaying results 571 - 580 of 10000 in total
  1. Drug

    Nebivolol

    go.drugbank.com/drugs/DB04861
    ApprovedInvestigational

    [A182594] Nebivolol was granted FDA approval on 17 December 2007.[L7985] … [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than [atenolol], [propranolol], or [pindolol].

    Mixtures: NEBIVOLOLO E IDROCLOROTIAZIDE EG, NEBIVOLOLO E IDROCLOROTIAZIDE EGProducts: NEBIVOLOLO EG, NEBIVOLOLO E IDROCLOROTIAZIDE ACCORD
  2. Drug

    Triclosan

    go.drugbank.com/drugs/DB08604
    Approved

    It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards … An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group.

    Mixtures: PREVENT 2 EN 1, T-Chem E2 RatedProducts: Antibacterial Spray Hand Soap/savon Antibacterien En Aerosol Pour Les Mains, Ben E. Keith Foaming Antibacterial Hand Cleaner
  3. Drug

    Capsaicin

    go.drugbank.com/drugs/DB06774
    ApprovedInvestigational

    Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements … Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations.

    Mixtures: NuDroxiPAK E-400, Trubrexa Patch ERSynonyms: (E)-8-Methyl-N-vanillyl-6-nonenamide, trans-8-Methyl-N-vanillyl-6-nonenamide
  4. Drug

    Citalopram

    go.drugbank.com/drugs/DB00215
    ApprovedInvestigational

    [A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 years or older.[L5230] … Citalopram is an antidepressant belonging to the class of selective _serotonin-reuptake inhibitors_ (SSRIs) widely used to treat the symptoms of depression.

    Products: CITALOPRAM EG, CITALOPRAM EG STADA
  5. Drug

    Ropinirole

    go.drugbank.com/drugs/DB00268
    ApprovedInvestigational

    In 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547]. … Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease.

    Products: ROPINIROLO EG, ROPINIROLO EG STADA
  6. Drug

    Lansoprazole

    go.drugbank.com/drugs/DB00448
    ApprovedInvestigational

    [A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD)

    Products: LANSOPRAZOLO EG, LANSOPRAZOLO EG STADA
  7. Drug

    Febuxostat

    go.drugbank.com/drugs/DB04854
    ApprovedInvestigational

    (CV) fatal outcomes in patients with gout and known cardiovascular disease treated with febuxostat, when compared to those treated with allopurinol. … [A39743] In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout.

    Products: FEBUXOSTAT EG
  8. Target

    Aggrecan core protein

    go.drugbank.com/bio_entities/BE0004104
    TargetHumans

    This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region

    Polypeptides: Aggrecan core proteinSynonyms: Cartilage-specific proteoglycan core protein, Chondroitin sulfate proteoglycan core protein 1
  9. Drug

    Lacosamide

    go.drugbank.com/drugs/DB06218
    ApprovedInvestigational

    [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved by the FDA in October 2008. … [A262681] It was granted approval by Health Canada in September 2010.[L49206]

    Synonyms: (R)-2-acetamido-N-benzyl-3- methoxypropionamide, (+)-(2R)-2-(ACETYLAMINO)-N-BENZYL-3-METHOXYPROPANAMIDEProducts: LACOSAMIDE EG, LASOMID IN
  10. Drug

    Phenytoin

    go.drugbank.com/drugs/DB00252
    ApprovedInvestigationalVet approved

    [A189219,A35884] Both parenteral and oral formulations of phenytoin are available on the market.[A189219] … [A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications

    Mixtures: GAMIBETAL COMPLEXProducts: Phenytoin ER