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Alizapride
go.drugbank.com/drugs/DB01425InvestigationalAlizapride is a dopamine antagonist that is capable of demonstrating both prokinetic and antiemetic effects. … This kind of pharmacological activity makes it effective for use in the treatment of various kinds of nausea and vomiting, including that which may occur postoperatively.
Categories: Dopamine D2 Receptor AntagonistsISIS 104838
go.drugbank.com/drugs/DB16201InvestigationalISIS 104838 is under investigation in clinical trial NCT00048321 (ISIS 104838, an Inhibitor of Tumor Necrosis Factor, for Active Rheumatoid Arthritis).
PRX-OTC
go.drugbank.com/drugs/DB17680ExperimentalPRX-OTC is an intracellular enzyme replacement therapy designed to replace missing or defective enzyme in patients with ornithine transcarbamylase deficiency.
AEOL-10150
go.drugbank.com/drugs/DB05874ExperimentalAEOL 10150 is developed by Aeolus as a therapeutic agents based on its proprietary small molecule catalytic antioxidants.
TRK-001
go.drugbank.com/drugs/DB18577InvestigationalTRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Anethole
go.drugbank.com/drugs/DB15916ApprovedWithdrawnCategories: Compounds used in a research, industrial, or household settingNM-702
go.drugbank.com/drugs/DB05505InvestigationalM-702 is an orally active inhibitor of phosphodiesterase and thromboxane synthetase. … It is estimated that about 6 million people suffer from intermittent claudication in the USA, with only 10 percent of these people currently receiving treatment.
Tanaproget
go.drugbank.com/drugs/DB04787ExperimentalTanaproget (NSP-989) is an investigational non-steroidal progestin. … It is a high affinity, high efficacy agonist of the progesterone receptor (PR) with a much more selective binding profile relative to most conventional progestins.
Cortisone
go.drugbank.com/drugs/DB14681InvestigationalIt has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. … It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)
Categories: Corticosteroid Hormone Receptor Agonists