This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Anethole is an excipient added to medications for flavouring.
- Generic Name
- Anethole
- DrugBank Accession Number
- DB15916
- Background
Not Available
- Type
- Small Molecule
- Groups
- Approved, Experimental
- Structure
Structure for Anethole (DB15916)
- Weight
- Average: 148.205
Monoisotopic: 148.088815006 - Chemical Formula
- C10H12O
- Synonyms
- (E)-Anethole
- Anise camphor
- Isoestragole
- trans-Anethole
- External IDs
- 224-052-0
- FEMA NO. 2086
- NSC-209529
Pharmacology
- Indication
Not Available
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Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Beech Nut Menthol Cough Drop Anethole (1.3 mg / loz) + Eucalyptus oil (0.97 mg / loz) + Levomenthol (5.1 mg / loz) Lozenge Oral Beta Brands Limited 1997-10-20 2005-05-16 Canada 
Beech-nut Menthol Cough Drops Anethole (1.3 mg / loz) + Eucalyptus oil (.97 mg / loz) + Levomenthol (5.1 mg / loz) Lozenge Oral Life Savers Canada, Division Of Hershey Canada Inc. 1979-12-31 1997-04-24 Canada Bentasil Cherry Anethole (2 mg / loz) + Levomenthol (3 mg / loz) Lozenge Oral Carter Horner Corp. 1998-07-20 2005-03-21 Canada Bentasil Green Anethole (0.01 %) + Eucalyptol (0.03 %) + Levomenthol (0.13 %) Lozenge Oral Carter Horner Corp. 1987-12-31 2004-07-09 Canada Bentasil Honey-lemon Anethole (2.2 mg / loz) + Levomenthol (1.3 mg / loz) Lozenge Oral Carter Horner Corp. 1998-07-20 2005-03-21 Canada Bentasil Red Anethole (.1 %) + Levomenthol (0.17 %) Lozenge Oral Carter Horner Corp. 1981-12-31 2001-07-18 Canada Bentasil Yellow Anethole (.12 % / loz) + Levomenthol (.07 % / loz) Lozenge Oral Carter Horner Corp. 1981-12-31 2001-07-18 Canada URINEX (Enteric-Coated) Soft Gelatin Capsules Anethole (4 mg) + Borneol (10 mg) + Camphene (15 mg) + Eucalyptol (3 mg) + Fenchone (4 mg) + alpha-Pinene (24.8 mg) + beta-Pinene (6.2 mg) Capsule, gelatin coated Oral Pharco Health Sdn. Bhd 2020-09-08 Not applicable Malaysia 
โรวาทีเน็ก Anethole (4 mg) + Borneol (10 mg) + Camphene (15 mg) + Eucalyptol (3 mg) + Fenchone (4 mg) + alpha-Pinene (24.8 mg) + beta-Pinene (6.2 mg) Capsule บริษัท ดีซีเอช ออริกา (ประเทศไทย) จำกัด 1987-05-22 Not applicable Thailand 
Categories
- Drug Categories
- Alkenes
- Allyl Compounds
- Benzene Derivatives
- Compounds used in a research, industrial, or household setting
- Diet, Food, and Nutrition
- Ethers
- Flavoring Agents
- Food
- Food Additives
- Food Ingredients
- Hydrocarbons, Acyclic
- Methyl Ethers
- Pharmaceutic Aids
- Pharmaceutical Preparations
- Phenols
- Phenyl Ethers
- Physiological Phenomena
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- Q3JEK5DO4K
- CAS number
- 4180-23-8
- InChI Key
- RUVINXPYWBROJD-ONEGZZNKSA-N
- InChI
- InChI=1S/C10H12O/c1-3-4-9-5-7-10(11-2)8-6-9/h3-8H,1-2H3/b4-3+
- IUPAC Name
- 1-methoxy-4-[(1E)-prop-1-en-1-yl]benzene
- SMILES
- COC1=CC=C(\C=C\C)C=C1
References
- General References
- FDA Thailand: Rowatinex (Anethole, Borneol, Camphene, Eucalyptol, Fenchone, Alpha-Pinene, Beta-Pinene) Capsule [Link]
- External Links
- KEGG Compound
- C10428
- ChemSpider
- 553166
- 17881
- ChEBI
- 35616
- ChEMBL
- CHEMBL452630
- ZINC
- ZINC000000967630
- Wikipedia
- Anethole
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Lozenge Oral Capsule, gelatin coated Oral Capsule - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.177 mg/mL ALOGPS logP 3.4 ALOGPS logP 2.94 ChemAxon logS -2.9 ALOGPS pKa (Strongest Basic) -4.8 ChemAxon Physiological Charge 0 ChemAxon Hydrogen Acceptor Count 1 ChemAxon Hydrogen Donor Count 0 ChemAxon Polar Surface Area 9.23 Å2 ChemAxon Rotatable Bond Count 2 ChemAxon Refractivity 47.88 m3·mol-1 ChemAxon Polarizability 17.46 Å3 ChemAxon Number of Rings 1 ChemAxon Bioavailability 1 ChemAxon Rule of Five Yes ChemAxon Ghose Filter No ChemAxon Veber's Rule Yes ChemAxon MDDR-like Rule No ChemAxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at November 23, 2020 14:21 / Updated at May 07, 2021 21:08