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Verzistobart
go.drugbank.com/drugs/DB18895InvestigationalVerzistobart is under investigation in clinical trial NCT06056895 (Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma).
GC-373
go.drugbank.com/drugs/DB15797ExperimentalThe results showed potent inhibition of the target, suggesting that GC-373 holds therapeutic potential for Covid-19[A219036]. … GC-373 has been shown to inhibit the M<sup>pro</sup> target in various coronavirus strains, including feline, mink, and ferret M<sup>pro</sup> [A219041].
Categories: Experimental Unapproved Treatments for COVID-19Interferon Gamma
go.drugbank.com/drugs/DB15753InvestigationalInterferon gamma is a Type 1 inflammatory cytokine and the only type II interferon. It has antitumor properties, antiviral activities, and important immunoregulatory functions. … The interferon is primarily produced by activated T lymphocytes and natural killer cells.
Synonyms: IFN-G, IFN-γCrenolanib
go.drugbank.com/drugs/DB11832InvestigationalCrenolanib is under investigation for the treatment of Diffuse Intrinsic Pontine Glioma and Progressive or Refractory High-Grade Glioma.
Agerafenib
go.drugbank.com/drugs/DB15068InvestigationalAgerafenib is under investigation in clinical trial NCT03052569 (Expanded Access to RXDX-105 for Cancers With RET Alterations).
24-Homo-1,25-dihydroxyvitamin D3
go.drugbank.com/drugs/DB15557Experimental24-Homo-1,25-dihydroxyvitamin D3 is a novel [vitamin D] analogue.
Mixtures: Natal-V RX Multi-vitamin/Multi-mineralArabica coffee bean
go.drugbank.com/drugs/DB10666ApprovedArabica coffee bean allergenic extract is used in allergenic testing.
Categories: Non-Standardized Food Allergenic Extract, Non-Standardized Plant Allergenic ExtractPoloxalene
go.drugbank.com/drugs/DB11451InvestigationalVet approvedEthylene oxide/propylene oxide copolymer is used as a food additive. It belongs to the family of Epoxides.
Categories: Compounds used in a research, industrial, or household settingInolimomab
go.drugbank.com/drugs/DB15628InvestigationalIt has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.[A241385] … Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease.
Adenosine 5'-[gamma-thio]triphosphate
go.drugbank.com/drugs/DB02930ExperimentalA nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group is replaced by sulfur.
Synonyms: Adenosine 5-O-(3-thiotriphophate), Adenosine 5'-O-(3-thiotriphosphate)Categories: Compounds used in a research, industrial, or household setting