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mRNA-3705
go.drugbank.com/drugs/DB17668InvestigationalmRNA-3705 is an investigational mRNA encoding methylmalonic CoA mutase (MUT) enzyme. Developed by Moderna TX Inc., it is being investigated for the treatment of methylmalonic academia.[A258843]
Mitiperstat
go.drugbank.com/drugs/DB18963InvestigationalMitiperstat is under investigation in clinical trial NCT05492877 (An Efficacy and Safety Study of Mitiperstat (AZD4831) (MPO Inhibitor) vs Placebo in the Treatment of Moderate to Severe COPD.).
MM-093
go.drugbank.com/drugs/DB05512InvestigationalMM-093 is a recombinant version of human alpha-fetoprotein (hAFP), an immunomodulatory serum protein normally produced at very high levels by the fetus and present in low levels in the blood of adults … Research on AFP suggests that it may play a role in modulating the immune system of the mother in order to protect the developing fetus during pregnancy.
NKG2D-ACE2 CAR-NK Cell
go.drugbank.com/drugs/DB15727InvestigationalChimeric antigen receptors (CARs) are artificial receptors consisting of an antibody-derived antigen binding domain and transmembrane and signaling domains from T-cell receptor signalling moieties. … The ACE2 is a receptor for SARS-Cov-2, binding to the S-protein of the viral envelope and competitively inhibiting SARS-Cov-2 infection of type II alveolar epithelial cells.
Synonyms: ACE2 CAR-NK Cell, NKG2D CAR-NK CellAsiatic acid
go.drugbank.com/drugs/DB14054InvestigationalFrom Centella asiatica and other plants; shows a variety of bioactivities.
Mixtures: Karatica Im Cica Essence PackCarbenoxolone
go.drugbank.com/drugs/DB02329ExperimentalAn agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. … Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity. [PubChem]
Teclozan
go.drugbank.com/drugs/DB13205InvestigationalTeclozan is an antiprotozoal agent employed typically as a therapy to treat protozoan infections.
Satricabtagene autoleucel
go.drugbank.com/drugs/DB18288InvestigationalSatricabtagene autoleucel is an autologous CAR T-cell product candidate against protein Claudin18.2 (CLDN18.2).
7MW3711
go.drugbank.com/drugs/DB19298InvestigationalDeveloped by Mabwell, 7MW3711 is an antibody-drug conjugate targeting B7-H3.[L50918,L50923]
Dimenoxadol
go.drugbank.com/drugs/DB01461ExperimentalIllicitDimenoxadol is an opioid analgesic which produces typical opioid effects such as analgesia and sedation. It is structurally similar to methadone and is a benzilic acid derivative. … In the United States it is classified as a Schedule I controlled drug.