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Displaying results 5871 - 5880 of 10000 in total
  1. Drug

    Gantofiban

    go.drugbank.com/drugs/DB20951
    Experimental

    Gantofiban has a monoisotopic molecular weight of 447.21 Da. … The usage of the INN stem '-fiban' in the name indicates that Gantofiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).

  2. Drug

    Zerencotrep

    go.drugbank.com/drugs/DB21710
    Experimental

    Zerencotrep has a monoisotopic molecular weight of 524.11 Da. … The usage of the INN stem '-cotrep' in the name indicates that Zerencotrep is a transient receptor potential canonical channel 5 (TRPC5) antagonist.

  3. Drug

    CTx-PDE6b

    go.drugbank.com/drugs/DB17858
    Investigational

    Being commercialied by Coave Therapeutics, it is being investigated for the treatment of retinitis pigmentosa due to _PDE6b_ gene mutations.[L46757] … CTx-PDE6b is an adeno-associated virus (AAV) based gene therapy designed to deliver a full-length non-mutated copy of the functional human _PDE6b_ gene.

  4. Drug

    QRX-411

    go.drugbank.com/drugs/DB17868
    Experimental

    It addresses the underlying cause of Usher syndrome due to the c.7595-2144A>G mutation in the _USH2A_ gene.[L46777] … QRX-411 is a first-in-class RNA-based oligonucleotide designed to restore wild-type USH2A mRNA, leading to the production of the functional USH2A protein.

  5. Drug

    Rumex acetosella whole

    go.drugbank.com/drugs/DB14166
    ApprovedWithdrawn

    Rumex acetosella whole allergenic extract is used in allergenic testing.

  6. Drug

    Rumex crispus top

    go.drugbank.com/drugs/DB14167
    ApprovedWithdrawn

    Rumex crispus top allergenic extract is used in allergenic testing.

  7. Drug

    Salix nigra bark

    go.drugbank.com/drugs/DB14169
    ApprovedWithdrawn

    Salix nigra bark allergenic extract is used in allergenic testing.

  8. Drug

    Edaxeterkib

    go.drugbank.com/drugs/DB21490
    Investigational

    Edaxeterkib is under investigation in clinical trial NCT03051035 (First-in-Human Study of KO-947 in Non-Hematological Malignancies). Edaxeterkib has a monoisotopic molecular weight of 469.22 Da. … The usage of the INN stem '-terkib' in the name indicates that Edaxeterkib is a extracellular signal-regulated kinase (ERK) inhibitor.

  9. Drug

    Neladalkib

    go.drugbank.com/drugs/DB21712
    Investigational

    Neladalkib has a monoisotopic molecular weight of 452.15 Da. … The usage of the INN stem '-alkib' in the name indicates that Neladalkib is a ALK (anaplastic lymphoma kinase) inhibitor.

    Synonyms: an orally bioavailable ALK inhibitor (a macrocyclic compound containing nitrogen heterocycles)
  10. Drug

    CERE-110

    go.drugbank.com/drugs/DB05898
    Investigational

    CERE-110 is a gene-therapy product that involves in vivo delivery of nerve growth factor (NGF) genes through an adeno-associated viral vector (AAV) delivery system.