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Displaying results 581 - 590 of 10000 in total
  1. Drug

    Lisinopril

    go.drugbank.com/drugs/DB00722
    ApprovedInvestigational

    [A184781,A184808,A184817] ACEIs are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. … [A184844] Lisinopril was granted FDA approval on 29 December 1987.[L8384]

    Mixtures: Nu-lisinopril/hctz, Nu-lisinopril/hctzCategories: Agents Acting on the Renin-Angiotensin System, Compounds used in a research, industrial, or household setting
  2. Drug

    Glasdegib

    go.drugbank.com/drugs/DB11978
    ApprovedInvestigational

    [A258493] Aberrant of Hh signaling is one of the main pathophysiologies of AML, with observed overexpression or constitutive activation of SMO. … [A40310] The great lipophilicity of this group of compounds brought interest to further modification.

  3. Drug

    Casimersen

    go.drugbank.com/drugs/DB14984
    ApprovedInvestigational

    on further verification in confirmatory trials. … Casimersen was granted accelerated FDA approval on February 25, 2021, based on data showing an increase in dystrophin levels in skeletal muscle of patients treated with casimersen; this approval is contingent

    Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    Balsam of Peru

    go.drugbank.com/drugs/DB11482
    ApprovedNutraceuticalVet approved

    [L2879] By Health Canada, the balsam of Peru is approved by the use of over-the-counter combination products and it is currently approved in veterinary products. … Balsam of Peru is a resin that comes from the tree Myroxylon balsamum pereirae. It is constituted by a mixture of substances from which the major components are benzyl cinnamate and [DB00676].

    Synonyms: Balsam-of-peru oil, Balsam of Peru essential oilMixtures: Keloid Healer Synergy for treatment of keloids, DERIVERIN MERHEM, 25 G
  5. Drug

    Prednisolone phosphate

    go.drugbank.com/drugs/DB14631
    ApprovedInvestigationalVet approved

    [A187463] Prednisolone phosphate was granted FDA Approval on 19 December 1973.[L14144]

    Products: PREDNISOLONA 1 MG/ ML, XILONE Syrup 5 mg / 5 ml
  6. Drug

    CHF 4227

    go.drugbank.com/drugs/DB05882
    Experimental

    Additionally, the compound has shown no uterotrophic activity suggesting a potential therapeutic advantage over drugs normally used in postmenopausal therapy. … The compound has a high receptor affinity and has shown promising efficacy in the prevention of bone loss in animal models of osteoporosis.

  7. Drug

    Colfosceril palmitate

    go.drugbank.com/drugs/DB09114
    ApprovedWithdrawn

    [A31510] It was part of the first generation of commercially available artificial surfactants.[T70] It was developed by Burroughs Wellcome and it was FDA approved on August 6, 1990. … [L1109] Nowadays colfosceril palmitate is under the state of canceled post-marketing.

  8. Drug

    Prednisolone acetate

    go.drugbank.com/drugs/DB15566
    ApprovedInvestigationalVet approved

    Prednisolone acetate is a prednisolone molecule bound to an acetate functional group by an ester bond. Prednisolone acetate was granted FDA approval in 1955.

    Mixtures: Pred-G, Pred-GProducts: PREDNISOLONE ACETATE SUSPENSION 25 mg/ml, Prednifluid 10 mg/ml Augentropfensuspension
  9. Drug

    Medium-chain triglycerides

    go.drugbank.com/drugs/DB13959
    ApprovedInvestigational

    Medium-chain triglycerides (MCTs) are triglycerides made up of a glycerol backbone and three fatty acids with an aliphatic tail of six to 12 carbon atoms. … [A246688] MCTs are used in parenteral nutrition therapy: they serve as a source of calories and essential fatty acids in conditions associated with malnutrition and malabsorption.[L41340]

    Mixtures: SMOFlipid 200 mg/ml Emulsion zur InfusionSynonyms: Fractionated triglyceride of coconut oil
  10. Drug

    Trospium

    go.drugbank.com/drugs/DB00209
    ApprovedInvestigational

    [L6208] An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes, loss of control over urination. … Trospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably.

    International brands: Tropez ODProducts: SPASMOLYT 15 MG, TROSBIO® 30 MG