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Trospium is an antimuscarinic agent used to treat the symptoms of overactive bladder (OAB). An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes, loss of control over urination.
- Mechanism
- Curator reviewed
Trospium antagonizes the effect of acetylcholine on muscarinic receptors in cholinergically innervated organs. Its parasympatholytic action reduces the tonus of smooth muscle in the bladder.
- Primary indication
- Trospium is indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency.Curator reviewed · 2 structured indications
- Formula / weight
- C25H30NO3 · 392.518 g/mol (avg)
- First approval
- Canada, 2010 · United States, 2007
- Brand names
- Cobenfy
Resolves to
Clinical / RWD
Structure
InChIKey
OYYDSUSKLWTMMQ-JKHIJQBDSA-NSMILES[H][C@]12CC[C@]([H])(C[C@@H](C1)OC(=O)C(O)(C1=CC=CC=C1)C1=CC=CC=C1)[N+]21CCCC1What you can answer from here — as of September 13, 2026
4Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
Which drugs share a target with Trospium, and which of those have an active Phase 3 trial?