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Simvastatin
go.drugbank.com/drugs/DB00641ApprovedInvestigational[A181090,A181093,A181096,A181427,A181475,A181538] Statins are considered a cost-effective treatment option for CVD due to their evidence of reducing all-cause mortality including fatal and non-fatal CVD … [A181087, A181406] Increasing use of the statin class of drugs is largely due to the fact that cardiovascular disease (CVD), which includes heart attack, atherosclerosis, angina, peripheral artery disease
Mixtures: EXOTIB-DUOProducts: Nu-simvastatin Tablets, Ag-simvastatinPrednisolone acetate
go.drugbank.com/drugs/DB15566ApprovedInvestigationalVet approvedPrednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond.[L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449]
Products: Ak Tate Oph Sus 1%Cilostazol
go.drugbank.com/drugs/DB01166ApprovedInvestigationalCilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia
Categories: Compounds used in a research, industrial, or household settingProducts: CILOSTAZOL AL 50MG TAB, CILOSTAZOL AL 100MG TABKetorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigational[L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511] … Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution.
Mixtures: ONEMER DT, DOLAC DUOProducts: Nu-ketorolac, Nu-ketorolac Ophthalmic SolutionCalcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalCalcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D<sub>3</sub>, 1,25-dihydroxyvitamin … D<sub>3</sub>.
Categories: Vitamin D and AnaloguesSynonyms: 1α,25(OH)2D3, 1α,25-dihydroxyvitamin D3Betahistine
go.drugbank.com/drugs/DB06698ApprovedInvestigational[A220333,L16403] Betahistine was first approved by the FDA in the 1970s but withdrawn within approximately 5 years due to a lack of evidence supporting its efficacy. … It has a significant impact on both the physical and social functioning of affected individuals.
Products: BETAHISTIN AL 6, BETAHISTIN AL 12Guanfacine
go.drugbank.com/drugs/DB01018ApprovedInvestigationalGuanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension[L11274] but is now indicated as an extended release … tablet for the treatment of ADHD.
Products: Ag-guanfacine XRSitagliptin
go.drugbank.com/drugs/DB01261ApprovedInvestigationalThe effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255]. … Sitagliptin was granted FDA approval on October 16, 2006[L6061].
Mixtures: ARGLIPTIN-D, LIBERECO-DXProducts: SITAGLIPTIN DZ, Ag-sitagliptinMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalDiabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. … It can also be used to prevent nausea or vomiting associated with chemotherapy or certain surgical or diagnostic procedures.
Categories: Dopamine D2 Receptor Antagonists, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamideEntecavir
go.drugbank.com/drugs/DB00442ApprovedInvestigationalEntecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS). … Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine
Products: ENTECAVIR DR. REDDY'S, ENTECAVIR AL 1MG