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Domperidone
go.drugbank.com/drugs/DB01184ApprovedInvestigationalVet approvedIt speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Categories: Dopamine D2 Receptor AntagonistsPipequaline
go.drugbank.com/drugs/DB13991ExperimentalPipequaline is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. … Due to these differences, this drug is classified as a nonbenzodiazepine anxiolytic.
Minzasolmin
go.drugbank.com/drugs/DB18961InvestigationalMinzasolmin is under investigation in clinical trial NCT05543252 (An Extension Study to Evaluate the Long-term Efficacy, Safety and Tolerability of Minzasolmin (UCB0599) in Study Participants With Parkinson's
Nemiralisib
go.drugbank.com/drugs/DB16253InvestigationalNemiralisib is under investigation in clinical trial NCT03345407 (Dose Finding Study of Nemiralisib (GSK2269557) in Subjects With an Acute Moderate or Severe Exacerbation of Chronic Obstructive Pulmonary
Mesoridazine
go.drugbank.com/drugs/DB00933ApprovedWithdrawnA phenothiazine antipsychotic with effects similar to chlorpromazine.
Categories: Dopamine D2 Receptor Antagonists, Serotonin Receptor AntagonistsSparfosic acid
go.drugbank.com/drugs/DB03459ExperimentalSparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen atom. … This substance is known to target aspartate carbamoyltransferase catalytic chain and CAD protein.
NP-6A4
go.drugbank.com/drugs/DB17599ExperimentalNP-6A4 is a peptide designed to specifically bind and activate angiotensin II receptor type 2 (AT2R). It has an Orphan Drug designation from the FDA for pediatric cardiomyopathy.[A258523]
Insulin-like growth factor II
go.drugbank.com/drugs/DB14472InvestigationalTo perform its biological activities, this growth factor can present some dependence to [somatotropin]. … It is believed to be a major fetal growth factor in contrast to insulin-like growth factor I, which is a major growth factor in adults.
Synonyms: IGF-II, Insulin-like growth factor IIPF-08046040
go.drugbank.com/drugs/DB17555InvestigationalSEA-CD70 is an investigational humanized, non-fucosylated monoclonal antibody targeting CD70. … SEA-CD70 is under investigation in clinical trial NCT04227847 (A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies).