Mesoridazine is a phenothiazine antipsychotic used to treat schizophrenia, organic brain disorders, alcoholism, and psychoneuroses. A phenothiazine antipsychotic with effects similar to chlorpromazine.
- Mechanism
- Curator reviewed
Based upon animal studies, mesoridazine, as with other phenothiazines, acts indirectly on reticular formation, whereby neuronal activity into reticular formation is reduced without affecting its intrinsic ability to activate the cerebral cortex. In addition, the phenothiazines exhibit at least part of their activities through depression of hypothalamic centers. Neurochemically, the phenothiazines are thought to exert their effects by a central adrenergic blocking action.
- Primary indication
- Used in the treatment of schizophrenia, organic brain disorders, alcoholism and psychoneuroses.Curator reviewed
- Formula / weight
- C21H26N2OS2 · 386.574 g/mol (avg)
- First approval
- Canada, 1997 · United States, 1994
- Also known as
- Thioridazine 2-sulfoxide · Thioridazine thiomethyl sulfoxide
- Code names
- NC-123 · TPS-23
Resolves to
SLVMESMUVMCQIY-UHFFFAOYSA-NSMILESCN1CCCCC1CCN1C2=C(SC3=C1C=C(C=C3)S(C)=O)C=CC=C2What you can answer from here — as of September 23, 2026
Which drugs share a target with Mesoridazine, and which of those have an active Phase 3 trial?
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