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Displaying results 5901 - 5910 of 9705 in total
  1. Drug

    TBX-3400

    go.drugbank.com/drugs/DB17370
    Investigational

    TBX-3400 is an investigational cell-based immunotherapy consisting of autologous peripheral blood mononuclear cells (PBMCs) treated ex vivo with TBX-4000, which is a recombinant TAT-MYC fusion protein.

  2. Drug

    Zanolimumab

    go.drugbank.com/drugs/DB17376
    Investigational

    Zanolimumab is a fully human monoclonal antibody directed against CD4.

  3. Drug

    MVR-T3011

    go.drugbank.com/drugs/DB17378
    Investigational

    MVR-T3011 is a genetically modified oncolytic Herpes Simplex Virus (HSV-1) with 2 exogenous genes encoding the active heterodimer human interleukin 12 (IL-12) and the Fab fragment of an anti-human PD-1

  4. Drug

    Nadofaragene firadenovec

    go.drugbank.com/drugs/DB17381
    ApprovedInvestigational

    Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). … [A255106,L44381] Nadofaragene firadenovec also has a manageable adverse event profile. Compared to [pembrolizumab], a smaller proportion of patients experienced grade 3-4 adverse events (4% vs 12.7%).

  5. Drug

    Xenon Xe-129

    go.drugbank.com/drugs/DB17386
    ApprovedInvestigational

    They undergo a process that increases nuclear polarization up to five orders of magnitude, leading to a higher MRI signal. … Hyperpolarized Xenon-129 (Xe-129) is a contrast agent used in the lung's clinical magnetic resonance imaging (MRI).

  6. Drug

    Becotatug vedotin

    go.drugbank.com/drugs/DB17407
    Investigational

    MRG-003 is a recombinant humanized anti-human epidermal growth factor receptor monoclonal antibody conjugated to monomethyl auristatin E.

  7. Drug

    TNG908

    go.drugbank.com/drugs/DB17411
    Investigational

    TNG908 is a small molecule inhibitor of protein arginine methyl transferase 5 (PRMT5).

  8. Drug

    SCH-58500

    go.drugbank.com/drugs/DB17416
    Investigational

    SCH-58500 is a recombinant replication-deficient adenovirus vector carrying the human p53 gene.

  9. Drug

    MT-0169

    go.drugbank.com/drugs/DB17430
    Investigational

    MT-0169 is a usion protein comprised of an enzymatically active Shiga-like toxin-I A1 subunit fused to a human single chain variable fragment with affinity for human CD38 cell surface protein.

  10. Drug

    Lym-1-I-131

    go.drugbank.com/drugs/DB17445
    Experimental

    Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant lymphocytes.