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Displaying results 5901 - 5910 of 10000 in total
  1. Drug

    Drotrecogin alfa

    go.drugbank.com/drugs/DB00055
    ApprovedWithdrawn

    It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. … Drotrecogin alfa was withdrawn from the market after a major study indicated that it was not effective in improving outcomes in patients with sepsis.

  2. Drug

    Cergutuzumab amunaleukin

    go.drugbank.com/drugs/DB14874
    Investigational

    Cergutuzumab amunaleukin is under investigation in clinical trial NCT02004106 (A Study to Evaluate Safety, Pharmacokinetics, and Efficacy of RO6895882 in Participants With Advanced and/or Metastatic Solid

  3. Drug

    Zalifrelimab

    go.drugbank.com/drugs/DB15632
    Investigational

    Zalifrelimab is under investigation in clinical trial NCT03894215 (Phase 2 Study of Anti-pd-1 Independently or in Combination With Anti-ctla-4 in Second-line Cervical Cancer).

    Synonyms: A human monoclonal antibody targeting cytotoxic T lymphocyte associated protein 4 (ctla4)
  4. Drug

    Bisphosphocin Nu-3

    go.drugbank.com/drugs/DB16015
    Investigational

    Bisphosphocin Nu-3 is under investigation in clinical trial NCT02737722 (Topically Applied Bisphosphocin Nu-3 on Infected Diabetic Ulcers of Subjects With Type I or II Diabetes Mellitus).

  5. Drug

    Duvakitug

    go.drugbank.com/drugs/DB19444
    Investigational

    Duvakitug is under investigation in clinical trial NCT05668013 (A Study to Evaluate the Long-term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease).

  6. Drug

    Emetonium iodide

    go.drugbank.com/drugs/DB13769
    Experimental

    Categories: Drugs for Functional Gastrointestinal Disorders
  7. Drug

    Imazodan

    go.drugbank.com/drugs/DB20144
    Experimental

    Imazodan has a monoisotopic molecular weight of 240.1 Da. … Imazodan is a small molecule drug. The usage of the INN stem '-dan' in the name indicates that Imazodan is a cardiac stimulant, pimobendan derivative.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    TGAAC94

    go.drugbank.com/drugs/DB06175
    Investigational

    tgAAC94 is a recombinant adeno-associated virus serotype 2 (AAV2) vector containing the cDNA for a human tumor necrosis factor receptor (TNFR)-immunoglobulin (IgG1) Fc fusion (TNFR:Fc) gene. … The Health Recombinant DNA Advisory Committee (RAC) concluded that a possible role of the gene transfer in this clinical course could not definitively be excluded due to the lack of data. [A264038]

  9. Drug

    Milatuzumab

    go.drugbank.com/drugs/DB12943
    Investigational

    Milatuzumab has been used in trials studying the treatment of Lupus Nephritis, Multiple Myeloma (MM), GVHD (Acute or Chronic), Myelodysplastic Syndrome, and Chronic Lymphocytic Leukemia, among others.

  10. Drug

    Zetomipzomib

    go.drugbank.com/drugs/DB16070
    Investigational

    Zetomipzomib is under investigation in clinical trial NCT04033926 (A Phase 2 Study of KZR-616 to Evaluate Safety and Efficacy in Patients With Active Polymyositis or Dermatomyositis).