Rasdegafusp alfa

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Rasdegafusp alfa
DrugBank Accession Number
DB15185
Background

Rasdegafusp alfa is under investigation in clinical trial NCT03206047 (Atezolizumab, Guadecitabine, and CDX-1401 Vaccine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer).

Type
Biotech
Groups
Investigational
Synonyms
  • Rasdegafusp alfa
External IDs
  • CDX-1401

Pharmacology

Indication

Not Available

Pharmacology
Reduce drug development failure rates
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Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
SU9AMV39DB
CAS number
1587257-96-2

References

General References
Not Available
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2Active Not RecruitingTreatmentCutaneous Melanoma / Mucosal Melanoma / Ocular Melanoma / Stage IIB Cutaneous Melanoma AJCC v6 and v7 / Stage IIC Cutaneous Melanoma AJCC v6 and v7 / Stage III Cutaneous Melanoma AJCC v7 / Stage IIIA Cutaneous Melanoma AJCC v7 / Stage IIIB Cutaneous Melanoma AJCC v7 / Stage IIIC Cutaneous Melanoma AJCC v7 / Stage IV Cutaneous Melanoma AJCC v6 and v71
2WithdrawnTreatmentNon-Small Cell Lung Carcinoma (NSCLC)1
1CompletedTreatmentAcute Myeloid Leukemia (AML) / Alkylating Agent-Related Acute Myeloid Leukemia / Chronic Myelomonocytic Leukemia (CMML) / Myelodysplastic Syndromes (MDS) / Refractory Anemia With Excess Blasts in Transformation1
1CompletedTreatmentAcute Myeloid Leukemia (AML) / Blasts 30 Percent or Less of Bone Marrow Nucleated Cells / Chronic Myelomonocytic Leukemia (CMML) / High-risk Myelodysplastic Syndrome (MDS) / Myelodysplastic Syndromes (MDS) / Refractory Anemia1
1CompletedTreatmentAdvanced Ovarian Cancer / Anaplastic Astrocytoma (AA) / Anaplastic Oligo-astrocytoma (AOA) / Anaplastic Oligodendroglioma (AO) / Breast Cancer Stage IIIc / Breast Cancer, Stage IIIB / Esophageal Cancer, Stage IV / Estrogen Receptor Negative / Estrogen Receptor Positive / Glioblastoma Multiforme (GBM) / Hormone Resistant Prostate Cancer / Melanoma (Skin) Stage IV / Recurrent Adult Brain Neoplasm / Recurrent Bladder Carcinoma / Recurrent Breast Carcinoma / Recurrent Colorectal Carcinoma / Recurrent Esophageal Carcinoma / Recurrent Gastric Carcinoma / Recurrent Hepatocellular Carcinoma / Recurrent Lung Carcinoma / Recurrent Melanoma / Recurrent Ovarian Carcinoma / Recurrent Prostate Carcinoma / Recurrent Uterine Corpus Carcinoma / Refractory, metastatic hormone-refractory Prostate cancer / Renal Cell Cancer Metastatic / Renal Cell Carcinoma Recurrent / Resectable Hepatocellular Carcinoma / Sarcomas / Stage IA Breast Cancer / Stage IA Ovarian Cancer / Stage IA Uterine Corpus Cancer / Stage IB Breast Cancer / Stage IB Ovarian Cancer / Stage IB Uterine Corpus Cancer / Stage IC Ovarian Cancer / Stage II Uterine Corpus Cancer / Stage IIA Breast Cancer / Stage IIA Lung Carcinoma / Stage IIA Ovarian Cancer / Stage IIB Breast Cancer / Stage IIB Esophageal Cancer / Stage IIB Lung Carcinoma / Stage IIB Ovarian Cancer / Stage IIB Skin Melanoma / Stage IIC Ovarian Cancer / Stage IIC Skin Melanoma / Stage IIIA Breast Cancer / Stage IIIA Esophageal Cancer / Stage IIIA Lung Carcinoma / Stage IIIA Ovarian Cancer / Stage IIIA Skin Melanoma / Stage IIIA Uterine Corpus Cancer / Stage IIIB Esophageal Cancer / Stage IIIB Ovarian Cancer / Stage IIIB Skin Melanoma / Stage IIIB Uterine Corpus Cancer / Stage IIIC Esophageal Cancer / Stage IIIC Ovarian Cancer / Stage IIIC Skin Melanoma / Stage IIIC Uterine Corpus Cancer / Stage IV Bladder Urothelial Carcinoma / Stage IV Prostate Cancer / Stage IVA Uterine Corpus Cancer / Stage IVB Uterine Corpus Cancer1
1, 2Active Not RecruitingTreatmentPlatinum-Resistant Fallopian Tube Carcinoma / Platinum-Resistant Ovarian Carcinoma / Platinum-Resistant Primary Peritoneal Carcinoma / Recurrent Fallopian Tube Carcinoma / Recurrent Ovarian Carcinoma / Recurrent Primary Peritoneal Carcinoma1
1, 2CompletedTreatmentAdvanced Malignancies1
1, 2CompletedTreatmentFallopian Tube Carcinoma / Ovarian Carcinoma / Primary Peritoneal Carcinoma1
1, 2TerminatedTreatmentUnresectable Stage III or Stage IV Melanoma1
1, 2WithdrawnTreatmentAdvanced Triple Negative Breast Cancer / Melanoma, Malignant / Mesotheliomas / Non-Small Cell Lung Carcinoma (NSCLC) / Small Cell Lung Cancer (SCLC) / Urothelial Cancer1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on May 20, 2019 14:57 / Updated on February 21, 2021 18:55