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MaxAdFVIII
go.drugbank.com/drugs/DB17713ExperimentalMaxAdFVIII is an adenoviral vector that expresses the full-length human Factor VIII (hFVIII) cDNA. First developed by GenStar, it is being investigated for the treatment of hemophilia.
Exbivirumab
go.drugbank.com/drugs/DB17747ExperimentalExbivirumab is an investigational monoclonal antibody. … It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.[A259202]
AVR-RD-04
go.drugbank.com/drugs/DB18644ExperimentalAVR-RD-04 is an investigational gene therapy for cystinosis. … It consists of autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin.
Synonyms: autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosinP-BCMA-101
go.drugbank.com/drugs/DB17371InvestigationalP-BCMA-101 is an autologous CAR-T therapy developed using Poseida’s piggyBac platform technology.
AAV-RPE65
go.drugbank.com/drugs/DB18343ExperimentalAAV-RPE65 is an adenovirus associated viral vector serotype 5 containing the human RPE65 gene
Epirizole
go.drugbank.com/drugs/DB08991ExperimentalEpirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain.
Selodenoson
go.drugbank.com/drugs/DB16325InvestigationalSelodenoson is under investigation in clinical trial NCT00040001 (Safety and Efficacy Study of an A1-adenosine Receptor Agonist to Slow Heart Rate in Atrial Fibrillation).
Aphidicolin
go.drugbank.com/drugs/DB17742ExperimentalAphidicolin is an antimitotic and antiviral metabolite of the mould _Cephalosporium aphidicola_. It inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162]