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Xaliproden
go.drugbank.com/drugs/DB06393InvestigationalCategories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT1 Receptor AntagonistsTTP889
go.drugbank.com/drugs/DB05131InvestigationalTTP889 is the only known selective small molecule inhibitor of Factor IX, a key enzyme of the intrinsic pathway of the blood coagulation system. … TTP889 has proven to be effective in preventing clot formation in several animal models of human disease, without any signs of the bleeding associated with traditional anticoagulants.
Bexotegrast
go.drugbank.com/drugs/DB16515InvestigationalPLN-74809 is a small-molecule that dually inhibits both α<sub>v</sub>β<sub>6</sub> and α<sub>v</sub>β<sub>1</sub> to treat both idiopathic pulmonary fibrosis (IPF) and primary sclerosing cholangitis (PSC … In addition, the compound is also currently in Phase 2a trials (NCT04565249) for the treatment of COVID-19 related acute respiratory distress syndrome[L31713].
Synonyms: (2S)-4-(2-METHOXYETHYL-(4-(5,6,7,8-TETRAHYDRO-1,8-NAPHTHYRIDIN-2-YL)BUTYL)AMINO)-2-(QUINAZOLIN-4-YLAMINO)BUTANOIC ACID, (S)-4-[(2-Methoxyethyl)[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butyl]amino]-2-[(quinazolin-4-yl)amino]butanoic acidEmpesertib
go.drugbank.com/drugs/DB19473InvestigationalEmpesertib has a monoisotopic molecular weight of 559.17 Da. … Empesertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Empesertib is a serine/threonine kinase inhibitor.
Ancremonam
go.drugbank.com/drugs/DB19710InvestigationalAncremonam has a monoisotopic molecular weight of 518.05 Da. … Ancremonam is a small molecule drug. The usage of the INN stem '-monam' in the name indicates that Ancremonam is a monobactam antibiotic.
Desoxycorticosterone pivalate
go.drugbank.com/drugs/DB01134ExperimentalVet approvedFederal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian. … Desoxycorticosterone pivalate is a mineralocorticoid hormone and an analog of desoxycorticosterone. It is white, odorless, and stable in air.
International brands: Cortexone M, Percorten MCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDefoslimod
go.drugbank.com/drugs/DB20763InvestigationalDefoslimod has a monoisotopic molecular weight of 1148.65 Da. … Defoslimod is a small molecule drug. The usage of the INN stem '-imod' in the name indicates that Defoslimod is a immunomodulator, both stimulant/suppressive and stimulant.
Mevociclib
go.drugbank.com/drugs/DB21454InvestigationalMevociclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Mevociclib is a cyclin dependant kinase inhibitor. … Mevociclib is under investigation in clinical trial NCT03134638 (A Study of SY-1365 in Adult Patients With Advanced Solid Tumors). Mevociclib has a monoisotopic molecular weight of 586.26 Da.
Categories: Heterocyclic Compounds, 1-RingRisvodetinib
go.drugbank.com/drugs/DB21602InvestigationalRisvodetinib has a monoisotopic molecular weight of 574.28 Da. … Risvodetinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Risvodetinib is a tyrosine kinase inhibitor.