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Displaying results 51 - 60 of 31461 in total
  1. Drug

    Benazepril

    go.drugbank.com/drugs/DB00542
    ApprovedInvestigational

    Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836]. … Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837].

    Mixtures: CİBADREX 5/6,25 MG FİLM TABLET, 28 ADET, CİBADREX 10/12,5 MG FİLM TABLET, 28 ADETCategories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Nalotimagene carmaleucel

    go.drugbank.com/drugs/DB19155
    Investigational

    Synonyms: Cells are derived from the haematopoietic stem cell (HSC) donor and are genetically modified ex vivo with a non-replicative SFCMM-3 gamma- retroviral vector derived from Mo, human culture expanded activated allogeneic T cells for adjunctive immunotherapy.
  3. Drug

    Cenplacel-L

    go.drugbank.com/drugs/DB19188
    Investigational

    Cenplacel-L is under investigation in clinical trial (Study of Human Placenta-derived Cells (PDA001) to Evaluate the Safety and Effectiveness for Patients With Ischemic Stroke) for the treatment of patients

    Synonyms: ALLOGENEIC-UNRELATED PLACENTA-DERIVED STROMAL CELLS, EXPANDED EX VIVO, Cenplacel-L
  4. Drug

    Naproxen

    go.drugbank.com/drugs/DB00788
    ApprovedInvestigationalVet approved

    [A179098] Given its overall tolerability and effectiveness, naproxen can be considered a first line treatment for a variety of clinical situations requiring analgesia. … [A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile.

    Synonyms: (+)-(S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid, (S)-2-(6-Methoxy-2-naphthyl)propanoic acidInternational brands: Naprosyn EC, Bumaflex N
  5. Drug

    Barium sulfate

    go.drugbank.com/drugs/DB11150
    Approved

    It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield [L1957]. This drug is used as a contrast agent in diagnostic x-ray procedures. … Barium sulfate is ingested by mouth or administered rectally and combined with granules of effervescent bicarbonate to enhance distension of the GI tract, allowing for enhanced gastrointestinal tract visualization

    Mixtures: E-Z HD SULFATODE BARIO PARA SUSPENSION, E-Z HD SULFATODE BARIO PARA SUSPENSIONCategories: X-Ray Contrast Activity, X-Ray Contrast Media, Non-Iodinated
  6. Drug

    Metronidazole

    go.drugbank.com/drugs/DB00916
    ApprovedInvestigational

    Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. … A181036,A181039] Metronidazole has been used as an antibiotic for several decades[L7429], with added antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat a

    Synonyms: 1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole, 1-(β-ethylol)-2-methyl-5-nitro-3-azapyrroleInternational brands: Tricowas B
  7. Drug

    Valproic acid

    go.drugbank.com/drugs/DB00313
    ApprovedInvestigational

    Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. … [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century.

    Mixtures: Depakine Chronosphere 250 mg Retardgranulat in Beuteln, Depakine Chronosphere 250 mg Retardgranulat in BeutelnCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
  8. Drug

    Tapentadol

    go.drugbank.com/drugs/DB06204
    ApprovedInvestigational

    Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake. … [A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesSynonyms: 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol, PHENOL, 3-((1R,2R)-3-(DIMETHYLAMINO)-1-ETHYL-2-METHYLPROPYL)-
  9. Drug

    Ascorbic acid

    go.drugbank.com/drugs/DB00126
    ApprovedInvestigationalNutraceutical

    Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant. … A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables.

    Synonyms: Vitamin C, Vitamin-CMixtures: COD-C 500/250 MG EFERVESAN TABLET, 20 ADET, COD-C 500/250 MG EFERVESAN TABLET, 30 ADET
  10. Drug

    Tetracycline

    go.drugbank.com/drugs/DB00759
    ApprovedInvestigationalVet approvedWithdrawn

    The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. … It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane causing intracellular components to leak from bacterial cells.

    Synonyms: (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamideMixtures: Pylera 140 mg/125 mg/125 mg Hartkapseln, Pylera 140 mg/125 mg/125 mg Hartkapseln