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Thioproperazine
go.drugbank.com/drugs/DB01622ApprovedIt is virtually without antiserotonin and hypotensive action and has no antihistaminic property. … Thioproperazine has a marked cataleptic and antiapomorphine activity associated with relatively slight sedative, hypothermic and spasmolytic effects.
Categories: Adrenergic alpha-1 Receptor AntagonistsSynonyms: 2-dimethylsulfamido-(10-(3-1-methylpiperazinyl-4)propyl)-phenothiazine, N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine-2-sulfonamideMethotrexate
go.drugbank.com/drugs/DB00563ApprovedInvestigational[A180322] This inhibition leads to suppression of inflammation as well as prevention of cell division. … [L7180] Methotrexate was granted FDA approval on 7 December 1953.[L7198]
Categories: Heterocyclic Compounds, 2-RingSynonyms: 4-amino-10-methylfolic acid, 4-amino-N(10)-methylpteroylglutamic acidTopotecan
go.drugbank.com/drugs/DB01030ApprovedInvestigationalAn antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Categories: MATE 2 Substrates, MATE 2 Substrates with a Narrow Therapeutic IndexSynonyms: 9-[(dimethylamino)methyl]-10-hydroxy-(4S)-camptothecinMoricizine
go.drugbank.com/drugs/DB00680ApprovedWithdrawnAn antiarrhythmia agent used primarily for ventricular rhythm disturbances.
Synonyms: [10-(3-Morpholin-4-yl-propionyl)-10H-phenothiazin-2-yl]-carbamic acid ethyl ester, ethyl 10-(3-morpholinopropionyl)phenothiazine-2-carbamateCategories: Heterocyclic Compounds, 1-RingEstradiol
go.drugbank.com/drugs/DB00783ApprovedInvestigationalVet approved[L11485,L11488,L11491, L11494,L11497,L11500,L11503] When used for oral or IM administration, estradiol is commonly synthesized as a pro-drug ester (such as [DB13952], [DB13953], [DB13954], [DB13955 … Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain.
Mixtures: Angeliq 1 mg/2 mg Filmtabletten, ANGELIQ 1 MG/2 MG FILM KAPLI TABLET, 28 ADETSynonyms: (17β)-estra-1,3,5(10)-triene-3,17-diol, 17β-estra-1,3,5(10)-triene-3,17-diolNaloxegol
go.drugbank.com/drugs/DB09049ApprovedInvestigationalIt was approved by the FDA in September 2014 and is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non‑cancer pain.
Synonyms: (5α,6α)-17-Allyl-6-[(20-hydroxy-3,6,9,12,15,18-hexaoxaicos-1-yl)oxy]-4,5-epoxymorphinan-3,14-diolThioridazine
go.drugbank.com/drugs/DB00679ApprovedWithdrawnIt has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. … Thioridazine was withdrawn worldwide in 2005 due to its association with cardiac arrythmias.
Categories: Adrenergic alpha-1 Receptor AntagonistsSynonyms: 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine, 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazinePerphenazine
go.drugbank.com/drugs/DB00850ApprovedInvestigationalAn antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Mixtures: Etrafon 2 10, โพลีบอน 4-10Synonyms: 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol, 2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazineEstriol
go.drugbank.com/drugs/DB04573ApprovedInvestigationalVet approvedIt has also been approved and marketed throughout Europe and Asia for approximately 40 years for the treatment of post-menopausal hot flashes. … A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen.
Mixtures: GYNOFLOR 50 MG/0.03 MG VAJİNAL TABLET, 12 ADET, GYNOFLOR 50 MG/0.03 MG VAJİNAL TABLET, 6 ADETSynonyms: (16α,17β)-estra-1,3,5(10)-triene-3,16,17-triol, 1,3,5(10)-Estratriene-3,16-alpha,17beta-triol10-decarboxymethylaclacinomycin A
go.drugbank.com/drugs/DB01806ExperimentalSynonyms: 10-decarboxymethylaclacinomycin A