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Displaying results 591 - 600 of 5449 in total
  1. Drug

    Inebilizumab

    go.drugbank.com/drugs/DB12530
    ApprovedInvestigational

    [L14315] Given its mechanism of action and good safety profile, it may prove useful in the treatment of other conditions linked to autoimmune antibody production or B-cell malignancies. … [L52705,L14315] It is the first and only FDA-approved treatment for IgG4-RD.[L52705] In December 2025, the FDA approved an additional indication for generalized myasthenia gravis. [L54838]

  2. Drug

    Caspofungin

    go.drugbank.com/drugs/DB00520
    ApprovedInvestigational

    It is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall.

    Products: CASPOFUNGIN EG, KAFUM 50 MG/VIAL
  3. Drug

    Benserazide

    go.drugbank.com/drugs/DB12783
    ApprovedInvestigational

    A decarboxylase inhibitor like benserazide is consequently an effective compound to combine with levadopa as it is incapable of crossing the blood-brain barrier itself but acts to prevent the formation

    Mixtures: Restex 100 mg/25 mg Tabletten, Madopar 50 mg + 12,5 mg Kapsül
  4. Drug

    AMG-337

    go.drugbank.com/drugs/DB15639
    Investigational

    AMG-337 is under investigation in clinical trial NCT03147976 (QUILT-3.036: AMG 337 in Subjects With Advanced or Metastatic Solid Tumors).

  5. Drug

    Odevixibat

    go.drugbank.com/drugs/DB16261
    ApprovedInvestigational

    Odevixibat, or A4250, is an ileal sodium/bile acid cotransporter inhibitor indicated for the treatment of pruritus in patients older than 3 months, with progressive familial intrahepatic cholestasis (PFIC). Odevixibat is the first approv...

  6. Drug

    Donepezil

    go.drugbank.com/drugs/DB00843
    ApprovedInvestigational

    [L41125] Though it does not alter the progression of Alzheimer's disease, donepezil is effective in managing the symptoms of its associated dementia.[T668]

    Mixtures: DEMENT COMBI 10/5 MG + 10/10 MG + 10/15 MG + 10/20 MG AĞIZDA DAĞILAN TABLET TEDAVİYE BAŞLAMA PAKETİ, 28 ADET, DEMENT COMBI 10/5 MG + 10/10 MG + 10/15 MG + 10/20 MG AĞIZDA DAĞILAN TABLET TEDAVİYE BAŞLAMA PAKETİ, 28 ADETProducts: DONEPEZIL EG, DONEPEZIL-HCL - CT 5MG
  7. Drug

    Topiramate

    go.drugbank.com/drugs/DB00273
    ApprovedInvestigational

    [A175249] It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.

    Products: TOPIRAMATO EG, TOPAMAX (25 MG)
  8. Drug

    Aluminum chlorohydrate

    go.drugbank.com/drugs/DB11573
    Approved

    It is also used as a coagulant in the water purification process. … It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent.

    Products: Arrid Ext Dry Unscent Spray Aer 10%, Arrid Ext Dry Baby Fresh Scent Aer 10%
  9. Drug

    Levofloxacin

    go.drugbank.com/drugs/DB01137
    ApprovedInvestigational

    (i.e. it does not invert to the inactive isomer). … [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin[A190663] and remains stereochemically stable following administration

    Mixtures: TRILEVO 500 MG+30 MG+ 1000 MG TEDAVİ PAKETİProducts: LEVOFLOXACINA EG, LEVOFLOXACINA GET
  10. Drug

    Terlipressin

    go.drugbank.com/drugs/DB02638
    ApprovedInvestigational

    [A2601] It is a prodrug of [lypressin], or lysine vasopressin. Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor. … [A2601, A2602, A2603, A2604, A2605] It was also studied in hepatorenal syndrome (HRS) and variceal bleeding.[A252672] The drug was first approved by the FDA in September 2022.[L43217]

    Products: HAEMOPRESSIN® 1 MG, GLYPRESSIN ® 1 MG