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Displaying results 591 - 600 of 10000 in total
  1. Target

    Cytochrome b6-f complex subunit 6

    go.drugbank.com/bio_entities/BE0003907
    TargetMastigocladus laminosus

    PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex. … Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (PubMed:14526088

    Polypeptides: Cytochrome b6-f complex subunit 6Synonyms: Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI
  2. Target

    Trafficking protein particle complex subunit 6B

    go.drugbank.com/bio_entities/BE0004276
    TargetHumans

    Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic (PubMed:16025134, PubMed:16828797).

    Polypeptides: Trafficking protein particle complex subunit 6BSynonyms: TRAPP complex subunit 6B
  3. Target

    KAT8 regulatory NSL complex subunit 3

    go.drugbank.com/bio_entities/BE0009091
    TargetHumans

    Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites … The NSL complex also acts as a regulator of gene expression in mitochondria (PubMed:27768893).

    Polypeptides: KAT8 regulatory NSL complex subunit 3Synonyms: NSL complex protein NSL3
  4. Drug

    Calcitriol

    go.drugbank.com/drugs/DB00136
    ApprovedInvestigationalNutraceutical

    to [DB00146] in the liver and kidneys. … It is also available in topical form for the treatment of mild to moderate plaque psoriasis in adults.

    Products: CALCITRIOLO EG
  5. Drug

    Mycophenolate mofetil

    go.drugbank.com/drugs/DB00688
    ApprovedInvestigational

    It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA.[A180826] … [L7363] It is marketed by Roche Pharmaceuticals and was granted FDA approval for the prophylaxis of transplant rejection in 1995.

    Synonyms: 2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoateProducts: Mycophenolatmofetil Accord 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  6. Indication

    Uncomplicated Urinary Tract Infections caused by Citrobacter freundii complex

    go.drugbank.com/conditions/DBCOND0173161
    Drugs: Gepotidacin
    Synonyms: Uncomplicated Urinary Tract Infections caused by Citrobacter freundii complex
  7. Drug

    Dasatinib

    go.drugbank.com/drugs/DB01254
    ApprovedInvestigational

    [A2226] The use of dasatinib was first approved by the FDA in 2006.[L45171,L45186] … [A2226,A11377] Also, mutations in the kinase domain of BCR-ABL may lead to relapse during imatinib treatment.

    Synonyms: N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamideProducts: DASATINIB EG
  8. Drug

    Itraconazole

    go.drugbank.com/drugs/DB01167
    ApprovedInvestigational

    [L50051] Itraconazole was first approved in the US in 1992 [L50056] and is available orally. … While the intravenous formulation of the drug was formerly available, it was discontinued in the US in 2007.[A263232]

    Products: ITRACONAZOLO EG
  9. Drug

    Leuprolide

    go.drugbank.com/drugs/DB00007
    ApprovedInvestigational

    Prolonged activation of GnRHR results in significant downregulation of sex steroid levels, which is primarily responsible for the clinical efficacy of leuprolide in diverse conditions, including advanced … [L13781, L13790] Leuprolide remains frontline therapy in all conditions for which it is indicated for use.

    Products: ELIGARD 22.5 MG ENJ. COZ. ICIN S.C. TOZ ICEREN SIRINGA VE COZUCU ICEREN SIRINGA, 1 ADET
  10. Drug

    Metronidazole

    go.drugbank.com/drugs/DB00916
    ApprovedInvestigational

    It is available in capsule form, tablet form, and topical form, and suppository preparations for the treatment of various infections. … [A181036,A181039] Metronidazole has been used as an antibiotic for several decades[L7429], with added antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat

    Mixtures: METARSAL N CAPSULAS, FUROTIL-N (METRONIDAZOL 600MG NIFUROXAZIDE 200MG)Products: Flagyl ER, Florazole ER