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Allantoin
go.drugbank.com/drugs/DB11100ApprovedInvestigationalIn healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. … The concentration of allantoin in muscles increases from a resting value of about 5000 ug/kg to about 16000 ug/kg immediately after short-term exhaustive cycling exercise [FDA Label].
Mixtures: NOSKAR 100 MG/50 IU/10 MG / G, JEL 120 G, NOSKAR 100 MG/50 IU/10 MG / G, JEL 50 GProducts: Jilgyungyi (10 Tablets), Miracle GYN (10 Tablets)Cilostazol
go.drugbank.com/drugs/DB01166ApprovedInvestigationalCilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesProducts: CILOSTAZOL AL 50MG TAB, CILOSTAZOL AL 100MG TABTetracycline
go.drugbank.com/drugs/DB00759ApprovedInvestigationalVet approvedWithdrawnThe FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. … Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria.
Mixtures: Pylera 140 mg/125 mg/125 mg Hartkapseln, Pylera 140 mg/125 mg/125 mg HartkapselnCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsInsulin lispro
go.drugbank.com/drugs/DB00046ApprovedInvestigationalMarketed as the brand name product Humalog, insulin lispro begins to exert its effects within 15 minutes of subcutaneous administration, while peak levels occur 30 to 90 minutes after administration. … These biochemical changes result in a reduced tendency for self-association resulting in dissolution to a dimer and then to a monomer that is absorbed more rapidly after subcutaneous injection compared
Mixtures: HUMALOG MIX25 KWIKPEN 100 units/ml, HUMALOG MIX25 KWIKPEN 100 units/mlCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersLovastatin
go.drugbank.com/drugs/DB00227ApprovedInvestigational[A174553] More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid … [A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: LOVASTIN 20 MG TABLET, 15 ADET, LOVASTIN 40 MG TABLET, 15 ADETMivacurium
go.drugbank.com/drugs/DB01226ApprovedWithdrawnMivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. … It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.
Products: MIVACRON INJECTION 10 mg/5 ml, MİVACRON 10 MG/5 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADETTamsulosin
go.drugbank.com/drugs/DB00706ApprovedInvestigational[A178351] Tamsulosin was first approved by the FDA on April 15, 1997.[L6238] … Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.
Mixtures: Duodart 0,5 mg/0,4 mg Hartkapseln, DuTamsul 0,5 mg/0,4 mg HartkapselnCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesZinc oxide
go.drugbank.com/drugs/DB09321ApprovedInvestigationalZinc oxide is an inorganic compound used in a number of manufacturing processes. … It is also widely used to treat a variety of other skin conditions, in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments
Mixtures: Calcium Mg and Zn Capsules With Vitamin D, De LA Cruz Diaper RashCategories: Compounds used in a research, industrial, or household settingDarifenacin
go.drugbank.com/drugs/DB00496ApprovedInvestigationalDarifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions. … It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: Darifenacin 15 mg, ENABLEX 15 MGInfluenza B virus B/Hubei-Wujiagang/158/2009 BX-39 antigen (propiolactone inactivated)
go.drugbank.com/drugs/DB10780ApprovedWithdrawnA seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3.
Synonyms: influenza B virus B/Hubei Wujigang/158/2009/antigen, Influenza B virus B/Hubei-Wujiagang/158/2009 BX-39 antigen (propiolactone inactivated)